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Emerging various environmental threats to brain and overview of surveillance system with zebrafish model

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dc.contributor.author Vargas, Rafael
dc.contributor.author Ponce-Canchihuamán, Johny
dc.date.accessioned 2019-01-25T16:59:37Z
dc.date.available 2019-01-25T16:59:37Z
dc.date.issued 2017
dc.identifier.uri https://hdl.handle.net/20.500.12866/4900
dc.description.abstract Pathologies related to neurotoxicity represent an important percentage of the diseases that determine the global burden of diseases. Neurotoxicity may be related to the increasing levels of potentially neurotoxic agents that pollute the environment, which generates concern, since agents that affect children may increase the incidence of neurodevelopmental disorders, affecting the quality of life of future citizens. Many environmental contaminants have been detected, and many of them derive from several human activities, including the mining, agriculture, manufacturing, pharmaceutical, beverage and food industries. These problems are more acute in third world countries, where environmental regulations are lax or non-existent. An additional major emerging problem is drug contamination. Periodic monitoring should be performed to identify potential neurotoxic substances using biological tests capable of identifying the risk. In this sense the fish embryo test (FET), which is performed on zebrafish embryos, is a useful, reliable and economical alternative that can be implemented in developing countries. en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries Toxicology Reports
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Alprazolam en_US
dc.subject Arsenic en_US
dc.subject Atorvastatin en_US
dc.subject Environmental contaminants en_US
dc.subject Ethylene oxide en_US
dc.subject Global burden disease en_US
dc.subject Lead en_US
dc.subject Mercury en_US
dc.subject Methotrexate en_US
dc.subject Neurotoxicity en_US
dc.subject Phenythoin en_US
dc.subject Toluene en_US
dc.subject Trichlorethylene en_US
dc.subject Zebrafish embryo test en_US
dc.title Emerging various environmental threats to brain and overview of surveillance system with zebrafish model en_US
dc.type info:eu-repo/semantics/review
dc.identifier.doi https://doi.org/10.1016/j.toxrep.2017.08.002
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.01.07
dc.relation.issn 2214-7500


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