Universidad Peruana Cayetano Heredia

Epilepsy surgery and neurocysticercosis: Assessing the role of the cysticercotic lesion in medically-refractory epilepsy

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dc.contributor.author Escalaya, Alejandro L.
dc.contributor.author Burneo, Jorge G.
dc.date.accessioned 2019-01-25T16:59:38Z
dc.date.available 2019-01-25T16:59:38Z
dc.date.issued 2017
dc.identifier.uri https://hdl.handle.net/20.500.12866/4904
dc.description.abstract There is increasing evidence of the existence of refractoriness to treatment with antiepileptic medications in those with NCC-related epilepsy. We performed a systematic review with the objective to determine the role of a cysticercotic lesion in this group of patients. We sought those manuscripts, including case reports, describing patients with NCC-related medically-intractable epilepsy who underwent epilepsy surgery and were seizure-free a year after. Only 10 manuscripts fulfilled inclusion and exclusion criteria. Three different clinical presentations were identified: 1) the cysticercotic lesion was epileptogenic, 2) there was dual pathology, including the cysticercotic lesion, with the other lesion usually being hippocampal sclerosis, and 3) the cysticercotic lesion was not related to the epileptogenic focus. In the case of an epileptogenic cysticercotic lesion, the presence of gliosis appeared to be the culprit for epileptogenicity. More studies using large cohorts of patients might be able to confirm our findings. This article is part of a Special issue entitled "Neurocysticercosis and Epilepsy". en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries Epilepsy and Behavior
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Adult en_US
dc.subject Female en_US
dc.subject Humans en_US
dc.subject Male en_US
dc.subject Epilepsy en_US
dc.subject Neurocysticercosis en_US
dc.subject Epilepsy surgery en_US
dc.subject Anticonvulsants/therapeutic use en_US
dc.subject Drug Resistant Epilepsy/drug therapy/surgery en_US
dc.subject Epilepsy/drug therapy/surgery en_US
dc.subject Gliosis en_US
dc.subject Neurocysticercosis/complications/pathology en_US
dc.title Epilepsy surgery and neurocysticercosis: Assessing the role of the cysticercotic lesion in medically-refractory epilepsy en_US
dc.type info:eu-repo/semantics/review
dc.identifier.doi https://doi.org/10.1016/j.yebeh.2017.01.029
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.25
dc.relation.issn 1525-5069


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