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Revised diagnostic criteria for neurocysticercosis

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dc.contributor.author Del Brutto, O. H.
dc.contributor.author Nash, T. E.
dc.contributor.author White, A. C. Jr
dc.contributor.author Rajshekhar, V.
dc.contributor.author Wilkins, P. P.
dc.contributor.author Singh, G.
dc.contributor.author Vasquez, C. M.
dc.contributor.author Salgado, P.
dc.contributor.author Gilman, R. H.
dc.contributor.author Garcia, H. H.
dc.date.accessioned 2019-01-25T17:00:30Z
dc.date.available 2019-01-25T17:00:30Z
dc.date.issued 2016
dc.identifier.uri https://hdl.handle.net/20.500.12866/4949
dc.description.abstract BACKGROUND: A unified set of criteria for neurocysticercosis (NCC) has helped to standardize its diagnosis in different settings. METHODS: Cysticercosis experts were convened to update current diagnostic criteria for NCC according to two principles: neuroimaging studies are essential for diagnosis, and all other information provides indirect evidence favoring the diagnosis. Recent diagnostic advances were incorporated to this revised set. RESULTS: This revised set is structured in absolute, neuroimaging and clinical/exposure criteria. Absolute criteria include: histological confirmation of parasites, evidence of subretinal cysts, and demonstration of the scolex within a cyst. Neuroimaging criteria are categorized as major (cystic lesions without scolex, enhancing lesions, multilobulated cysts, and calcifications), confirmative (resolution of cysts after cysticidal drug therapy, spontaneous resolution of single enhancing lesions, and migrating ventricular cysts on sequential neuroimaging studies) and minor (hydrocephalus and leptomeningeal enhancement). Clinical/exposure criteria include: detection of anticysticercal antibodies or cysticercal antigens by well-standardized tests, systemic cysticercosis, evidence of a household Taenia carrier, suggestive clinical manifestations, and residency in endemic areas. Besides patients having absolute criteria, definitive diagnosis can be made in those having two major neuroimaging criteria (or one major plus one confirmative criteria) plus exposure. For patients presenting with one major and one minor neuroimaging criteria plus exposure, definitive diagnosis of NCC requires the exclusion of confounding pathologies. Probable diagnosis is reserved for individuals presenting with one neuroimaging criteria plus strong evidence of exposure. CONCLUSIONS: This revised set of diagnostic criteria provides simpler definitions and may facilitate its more uniform and widespread applicability in different scenarios. en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartof urn:issn:1878-5883
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Humans en_US
dc.subject Neurocysticercosis en_US
dc.subject Cysticercosis en_US
dc.subject Taenia solium en_US
dc.subject Diagnostic criteria, epilepsy, intracranial hypertension en_US
dc.subject Neuroimaging en_US
dc.subject Brain/diagnostic imaging en_US
dc.subject Neurocysticercosis/diagnosis en_US
dc.title Revised diagnostic criteria for neurocysticercosis en_US
dc.type info:eu-repo/semantics/review
dc.identifier.doi https://doi.org/10.1016/j.jns.2016.11.045
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.00 es_PE
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.25


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