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Childhood adversities and post-traumatic stress disorder: evidence for stress sensitisation in the World Mental Health Surveys

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dc.contributor.author McLaughlin, K. A.
dc.contributor.author Koenen, K. C.
dc.contributor.author Bromet, E. J.
dc.contributor.author Karam, E. G.
dc.contributor.author Liu, H.
dc.contributor.author Petukhova, M.
dc.contributor.author Ruscio, A. M.
dc.contributor.author Sampson, N. A.
dc.contributor.author Stein, D. J.
dc.contributor.author Aguilar-Gaxiola, S.
dc.contributor.author Alonso, J.
dc.contributor.author Borges, G.
dc.contributor.author Demyttenaere, K.
dc.contributor.author Dinolova, R. V.
dc.contributor.author Ferry, F.
dc.contributor.author Florescu, S.
dc.contributor.author de Girolamo, G.
dc.contributor.author Gureje, O.
dc.contributor.author Kawakami, N.
dc.contributor.author Lee, S.
dc.contributor.author Navarro-Mateu, F.
dc.contributor.author Piazza, M.
dc.contributor.author Pennell, B. E.
dc.contributor.author Posada-Villa, J.
dc.contributor.author ten Have, M.
dc.contributor.author Viana, M. C.
dc.contributor.author Kessler, R. C.
dc.date.accessioned 2019-01-25T17:02:40Z
dc.date.available 2019-01-25T17:02:40Z
dc.date.issued 2017
dc.identifier.uri https://hdl.handle.net/20.500.12866/4971
dc.description.abstract Background: Although childhood adversities are known to predict increased risk of post-traumatic stress disorder (PTSD) after traumatic experiences, it is unclear whether this association varies by childhood adversity or traumatic experience types or by age. Aims: To examine variation in associations of childhood adversities with PTSD according to childhood adversity types, traumatic experience types and life-course stage. Method: Epidemiological data were analysed from the World Mental Health Surveys (n=27017). Results: Four childhood adversities (physical and sexual abuse, neglect, parent psychopathology) were associated with similarly increased odds of PTSD following traumatic experiences (odds ratio (OR)=1.8), whereas the other eight childhood adversities assessed did not predict PTSD. Childhood adversity-PTSD associations did not vary across traumatic experience types, but were stronger in childhood-adolescence and early middle adulthood than later adulthood. Conclusions: Childhood adversities are differentially associated with PTSD, with the strongest associations in childhood-adolescence and early-middle adulthood. Consistency of associations across traumatic experience types suggests that childhood adversities are associated with generalised vulnerability to PTSD following traumatic experiences. en_US
dc.language.iso eng
dc.publisher Cambridge University Press
dc.relation.ispartof urn:issn:1472-1465
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject depression en_US
dc.subject Psychiatry en_US
dc.subject risk-factors en_US
dc.subject life events en_US
dc.subject psychiatric-disorders en_US
dc.subject psychopathology en_US
dc.subject national comorbidity survey en_US
dc.subject maltreatment en_US
dc.subject physical abuse en_US
dc.subject emotion regulation en_US
dc.subject adult recollections en_US
dc.title Childhood adversities and post-traumatic stress disorder: evidence for stress sensitisation in the World Mental Health Surveys en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1192/bjp.bp.116.197640
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.00 es_PE
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.24


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