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Obesity as a Conditioning Factor for High-Altitude Diseases

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dc.contributor.author San Martin, R.
dc.contributor.author Brito, J.
dc.contributor.author Siques, P.
dc.contributor.author León-Velarde, Fabiola
dc.date.accessioned 2019-01-25T17:02:41Z
dc.date.available 2019-01-25T17:02:41Z
dc.date.issued 2017
dc.identifier.uri https://hdl.handle.net/20.500.12866/4983
dc.description.abstract Obesity, a worldwide epidemic, has become a major health burden because it is usually accompanied by an increased risk for insulin resistance, diabetes, hypertension, cardiovascular diseases, and even some kinds of cancer. It also results in associated increases in healthcare expenditures and labor and economic consequences. There are also other fields of medicine and biology where obesity or being overweight play a major role, such as high-altitude illnesses (acute mountain sickness, hypoxic pulmonary hypertension, and chronic mountain sickness), where an increasing relationship among these two morbid statuses has been demonstrated. This association could be rooted in the interactions between obesity-related metabolic alterations and critical ventilation impairments due to obesity, which would aggravate hypobaric hypoxia at high altitudes, leading to hypoxemia, which is a trigger for developing high-altitude diseases. This review examines the current literature to support the idea that obesity or overweight could be major conditioning factors at high altitude. en_US
dc.language.iso eng
dc.publisher Karger
dc.relation.ispartofseries Obesity Facts
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject intermittent hypoxia en_US
dc.subject Obesity en_US
dc.subject Overweight en_US
dc.subject Hypoxia en_US
dc.subject risk-factors en_US
dc.subject Endocrinology & Metabolism en_US
dc.subject nutrition transition en_US
dc.subject Nutrition & Dietetics en_US
dc.subject illness en_US
dc.subject factors en_US
dc.subject acute mountain-sickness en_US
dc.subject body-mass index en_US
dc.subject Conditioning en_US
dc.subject energy-balance en_US
dc.subject fat distribution en_US
dc.subject High-altitude diseases en_US
dc.subject qinghai-tibet railroad en_US
dc.subject sea-level en_US
dc.title Obesity as a Conditioning Factor for High-Altitude Diseases en_US
dc.type info:eu-repo/semantics/review
dc.identifier.doi https://doi.org/10.1159/000477461
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.18
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.04
dc.relation.issn 1662-4033


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