Browsing Biología by Subject "rpoB"

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Determination of potentially novel compensatory mutations in rpoC associated with rifampin resistance and rpoB mutations in Mycobacterium tuberculosis clinical isolates from Peru

Vargas Ruiz, Ana Paula (Universidad Peruana Cayetano HerediaPE, 2020)

Background: Rifampicin (RIF) resistance in Mycobacterium tuberculosis is frequently caused by mutations in the rpoB gene. These mutations are associated with a fitness cost, which can be overcome by compensatory mutations ...