Hymenolepis nana Impact Among Children in the Highlands of Cusco, Peru: An Emerging Neglected Parasite Infection

García Lescano, Héctor Hugo; White, A. Clinton-Jr; Reynolds, Spencer-T.; Gotuzzo Herencia, José Eduardo; Lescano Guevara, Andres Guillermo; Vilchez, Elizabeth-C.; Lopez, Martha; Morales Fernández, María Luisa; Cabada, Miguel-M.

dc.contributor.author	Cabada, Miguel-M.
dc.contributor.author	Morales Fernández, María Luisa
dc.contributor.author	Lopez, Martha
dc.contributor.author	Reynolds, Spencer-T.
dc.contributor.author	Vilchez, Elizabeth-C.
dc.contributor.author	Lescano Guevara, Andres Guillermo
dc.contributor.author	Gotuzzo Herencia, José Eduardo
dc.contributor.author	García Lescano, Héctor Hugo
dc.contributor.author	White, A. Clinton-Jr
dc.date.accessioned	2019-02-06T14:45:11Z
dc.date.available	2019-02-06T14:45:11Z
dc.date.issued	2016
dc.identifier.uri	https://hdl.handle.net/20.500.12866/5036
dc.description.abstract	Hymenolepis nana is the most common cestode infection in the world. However, limited information is available regarding its impact on affected populations. We studied the epidemiology and symptoms associated with hymenolepiasis among children 3-16 years old in 16 rural communities of the highlands of the Cusco region in Peru. Information on demographics, socioeconomic status, symptoms as reported by parents, and parasitological testing was obtained from the database of an ongoing Fasciola hepatica epidemiologic study. A total of 1,230 children were included in the study. Forty-five percent were infected with at least one pathogenic intestinal parasite. Giardia spp. (22.9%) was the most common, followed by Hymenolepis (17.4%), Fasciola (14.1%), Ascaris lumbricoides (6.1%), and Strongyloides stercoralis (2%). The prevalence of Hymenolepis infection varied by community, by other parasitic infections, and by socioeconomic status. However, only years of education of the mother, use of well water, and age less than 10 years were associated with Hymenolepis infection in the multivariate analysis. Hymenolepis nana infection was associated with diarrhea, jaundice, headaches, fever, and fatigue. Children with > 500 eggs/g of stool were more likely to have symptoms of weight loss, jaundice, diarrhea, and fever. Hymenolepis nana infection and age were the only factors retained in the multivariate analysis modeling diarrhea. Hymenolepiasis is a common gastrointestinal helminth in the Cusco region and is associated with significant morbidity in children in rural communities. The impact caused by the emergence of Hymenolepis as a prevalent intestinal parasite deserves closer scrutiny.	en_US
dc.language.iso	eng
dc.publisher	American Society of Tropical Medicine and Hygiene
dc.relation.ispartofseries	American Journal of Tropical Medicine and Hygiene (ASTMH Journal)
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	Adolescent	en_US
dc.subject	Animals	en_US
dc.subject	Ascaris lumbricoides/isolation & purification	en_US
dc.subject	Child	en_US
dc.subject	Child, Preschool	en_US
dc.subject	Cross-Sectional Studies	en_US
dc.subject	Fasciola hepatica/isolation & purification	en_US
dc.subject	Feces/parasitology	en_US
dc.subject	Female	en_US
dc.subject	Humans	en_US
dc.subject	Hymenolepiasis/diagnosis/epidemiology	en_US
dc.subject	Hymenolepis nana/isolation & purification	en_US
dc.subject	Intestinal Diseases, Parasitic/diagnosis/epidemiology	en_US
dc.subject	Male	en_US
dc.subject	Multivariate Analysis	en_US
dc.subject	Peru/epidemiology	en_US
dc.subject	Prevalence	en_US
dc.subject	Socioeconomic Factors	en_US
dc.subject	Strongyloides stercoralis/isolation & purification	en_US
dc.title	Hymenolepis nana Impact Among Children in the Highlands of Cusco, Peru: An Emerging Neglected Parasite Infection	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.4269/ajtmh.16-0237
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn	1476-1645