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Prevalence of Pragmatically Defined High CV Risk and its Correlates in LMIC: A Report From 10 LMIC Areas in Africa, Asia, and South America

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dc.contributor.author Carrillo Larco, Rodrigo Martín
dc.contributor.author Miranda, J. Jaime
dc.contributor.author Li, Xian
dc.contributor.author Cui, Chendi
dc.contributor.author Xu, Xiaolin
dc.contributor.author Ali, Mohammed
dc.contributor.author Alam, Dewan-S.
dc.contributor.author Gaziano, Thomas-A.
dc.contributor.author Gupta, Rajeev
dc.contributor.author Irazola, Vilma
dc.contributor.author Levitt, Naomi-S.
dc.contributor.author Prabhakaran, Dorairaj
dc.contributor.author Rubinstein, Adolfo
dc.contributor.author Steyn, Krisela
dc.contributor.author Tandon, Nikhil
dc.contributor.author Xavier, Denis
dc.contributor.author Wu, Yangfeng
dc.contributor.author Yan, Lijing-L.
dc.date.accessioned 2019-02-06T14:45:11Z
dc.date.available 2019-02-06T14:45:11Z
dc.date.issued 2016
dc.identifier.uri https://hdl.handle.net/20.500.12866/5040
dc.description.abstract BACKGROUND: Currently available tools for assessing high cardiovascular risk (HCR) often require measurements not available in resource-limited settings in low- and middle-income countries (LMIC). There is a need to assess HCR using a pragmatic evidence-based approach. OBJECTIVES: This study sought to report the prevalence of HCR in 10 LMIC areas in Africa, Asia, and South America and to investigate the profiles and correlates of HCR. METHODS: Cross-sectional analysis using data from the National Heart, Lung, and Blood Institute-UnitedHealth Group Centers of Excellence. HCR was defined as history of heart disease/heart attack, history of stroke, older age (>/=50 years for men and >/=60 for women) with history of diabetes, or older age with systolic blood pressure >/=160 mm Hg. Prevalence estimates were standardized to the World Health Organization's World Standard Population. RESULTS: A total of 37,067 subjects ages >/=35 years were included; 53.7% were women and mean age was 53.5 +/- 12.1 years. The overall age-standardized prevalence of HCR was 15.4% (95% confidence interval: 15.0% to 15.7%), ranging from 8.3% (India, Bangalore) to 23.4% (Bangladesh). Among men, the prevalence was 1.7% for the younger age group (35 to 49 years) and 29.1% for the older group (>/=50); among women, 3.8% for the younger group (35 to 59 years) and 40.7% for the older group (>/=60). Among the older group, measured systolic blood pressure >/=160 mm Hg (with or without other conditions) was the most common criterion for having HCR, followed by diabetes. The proportion of having met more than 1 criterion was nearly 20%. Age, education, and body mass index were significantly associated with HCR. Cross-site differences existed and were attenuated after adjusting for age, sex, education, smoking, and body mass index. CONCLUSIONS: The prevalence of HCR in 10 LMIC areas was generally high. This study provides a starting point to define targeted populations that may benefit from interventions combining both primary and secondary prevention strategies. en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries Global Heart
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Developing Countries en_US
dc.subject Adult en_US
dc.subject Africa/epidemiology en_US
dc.subject Age Factors en_US
dc.subject Aged en_US
dc.subject Aged, 80 and over en_US
dc.subject Asia/epidemiology en_US
dc.subject Body Mass Index en_US
dc.subject Cardiovascular Diseases/epidemiology en_US
dc.subject Cross-Sectional Studies en_US
dc.subject Diabetes Mellitus/epidemiology en_US
dc.subject Educational Status en_US
dc.subject Female en_US
dc.subject Heart Diseases/epidemiology en_US
dc.subject Humans en_US
dc.subject Hypertension/epidemiology en_US
dc.subject Male en_US
dc.subject Middle Aged en_US
dc.subject Myocardial Infarction/epidemiology en_US
dc.subject Prevalence en_US
dc.subject Risk en_US
dc.subject Risk Factors en_US
dc.subject Sex Factors en_US
dc.subject Smoking/epidemiology en_US
dc.subject South America/epidemiology en_US
dc.subject Stroke/epidemiology en_US
dc.subject World Health Organization en_US
dc.title Prevalence of Pragmatically Defined High CV Risk and its Correlates in LMIC: A Report From 10 LMIC Areas in Africa, Asia, and South America en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1016/j.gheart.2015.12.004
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.04
dc.relation.issn 2211-8179


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