Substance Use and Adherence Among People Living with HIV/AIDS Receiving cART in Latin America

McGowan, Catherine-C.; Padgett, Denis; Gotuzzo Herencia, José Eduardo; Rebeiro, Peter-F.; Cortes, Claudia; De-Boni, Raquel-B.; Shepherd, Bryan-E.; Cesar, Carina; Grinsztejn, Beatriz; Belaunzaran-Zamudio, Pablo-F.; Duda, Stephany-N.

dc.contributor.author	De-Boni, Raquel-B.
dc.contributor.author	Shepherd, Bryan-E.
dc.contributor.author	Grinsztejn, Beatriz
dc.contributor.author	Cesar, Carina
dc.contributor.author	Cortes, Claudia
dc.contributor.author	Padgett, Denis
dc.contributor.author	Gotuzzo Herencia, José Eduardo
dc.contributor.author	Belaunzaran-Zamudio, Pablo-F.
dc.contributor.author	Rebeiro, Peter-F.
dc.contributor.author	Duda, Stephany-N.
dc.contributor.author	McGowan, Catherine-C.
dc.date.accessioned	2019-02-06T14:45:12Z
dc.date.available	2019-02-06T14:45:12Z
dc.date.issued	2016
dc.identifier.uri	https://hdl.handle.net/20.500.12866/5052
dc.description.abstract	This cross-sectional study describes substance use prevalence and its association with combination antiretroviral therapy (cART) adherence among 3343 individuals receiving care at HIV clinics in Argentina, Brazil, Chile, Honduras, Mexico, and Peru. A rapid screening tool evaluated self-reported 7-day recall of alcohol, marijuana, cocaine, heroin, and methamphetamine use, and missed cART doses. Overall, 29.3 % individuals reported having >/=1 alcoholic drinks, 5.0 % reported any illicit drug use and 17.0 % reported missed cART doses. In the logistic regression model, compared to no substance use, alcohol use [adjusted odds ratio (AOR) = 2.46, 95 % confidence interval (CI): 1.99-3.05], illicit drug use (AOR = 3.57, 95 % CI: 2.02-6.30), and using both alcohol and illicit drugs (AOR = 4.98, 95 % CI: 3.19-7.79) were associated with missed cART doses. The associations between substance use and likelihood of missing cART doses point to the need of targeting alcohol and illicit drug use to improve adherence among people living with HIV in Latin America.	en_US
dc.language.iso	eng
dc.publisher	Springer
dc.relation.ispartofseries	AIDS and Behavior
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	Adherence	en_US
dc.subject	HIV/AIDS	en_US
dc.subject	Latin America	en_US
dc.subject	Medication Adherence	en_US
dc.subject	Street Drugs	en_US
dc.subject	Substance use	en_US
dc.subject	Acquired Immunodeficiency Syndrome/drug therapy/epidemiology	en_US
dc.subject	Adult	en_US
dc.subject	Anti-HIV Agents/therapeutic use	en_US
dc.subject	Cross-Sectional Studies	en_US
dc.subject	Drug Therapy, Combination	en_US
dc.subject	Female	en_US
dc.subject	HIV Infections/drug therapy/epidemiology	en_US
dc.subject	Humans	en_US
dc.subject	Latin America	en_US
dc.subject	Male	en_US
dc.subject	Middle Aged	en_US
dc.subject	Odds Ratio	en_US
dc.subject	Substance-Related Disorders/epidemiology	en_US
dc.title	Substance Use and Adherence Among People Living with HIV/AIDS Receiving cART in Latin America	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.1007/s10461-016-1398-6
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.08
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.12
dc.relation.issn	1573-3254