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Symptoms and Immune Markers in Plasmodium/Dengue Virus Co-infection Compared with Mono-infection with Either in Peru

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dc.contributor.author Halsey, Eric-S.
dc.contributor.author Baldeviano, G. Christian
dc.contributor.author Edgel, Kimberly-A.
dc.contributor.author Vilcarromero, Stalin
dc.contributor.author Sihuincha, Moises
dc.contributor.author Lescano Guevara, Andres Guillermo
dc.date.accessioned 2019-02-06T14:45:35Z
dc.date.available 2019-02-06T14:45:35Z
dc.date.issued 2016
dc.identifier.uri https://hdl.handle.net/20.500.12866/5079
dc.description.abstract BACKGROUND: Malaria and dengue are two of the most common vector-borne diseases in the world, but co-infection is rarely described, and immunologic comparisons of co-infection with mono-infection are lacking. METHODOLOGY AND PRINCIPAL FINDINGS: We collected symptom histories and blood specimens from subjects in a febrile illness surveillance study conducted in Iquitos and Puerto Maldonado, Peru, between 2002-2011. Nineteen symptoms and 18 immune markers at presentation were compared among those with co-infection with Plasmodium/dengue virus (DENV), Plasmodium mono-infection, and DENV mono-infection. Seventeen subjects were identified as having Plasmodium/DENV co-infection and were retrospectively matched with 51 DENV mono-infected and 44 Plasmodium mono-infected subjects. Those with Plasmodium mono-infection had higher levels of IL-4, IL-6, IL-10, en_US
dc.language.iso eng
dc.publisher Public Library of Science
dc.relation.ispartofseries PLoS Neglected Tropical Diseases
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Adolescent en_US
dc.subject Adult en_US
dc.subject Biomarkers/blood en_US
dc.subject Child en_US
dc.subject Coinfection/pathology en_US
dc.subject Cough/pathology en_US
dc.subject Cytokines/blood en_US
dc.subject Dengue/complications/pathology en_US
dc.subject Female en_US
dc.subject Humans en_US
dc.subject Malaria/complications/pathology en_US
dc.subject Male en_US
dc.subject Middle Aged en_US
dc.subject Myalgia/pathology en_US
dc.subject Peru en_US
dc.subject Retrospective Studies en_US
dc.subject Young Adult en_US
dc.title Symptoms and Immune Markers in Plasmodium/Dengue Virus Co-infection Compared with Mono-infection with Either in Peru en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1371/journal.pntd.0004646
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn 1935-2735


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