Universidad Peruana Cayetano Heredia

Comparison of Recommendations in Clinical Practice Guidelines for Acute Gastroenteritis in Children

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dc.contributor.author Lo-Vecchio, Andrea
dc.contributor.author Dias, Jorge-Amil
dc.contributor.author Berkley, James-A.
dc.contributor.author Boey, Chris
dc.contributor.author Cohen, Mitchell-B.
dc.contributor.author Cruchet, Sylvia
dc.contributor.author Liguoro, Ilaria
dc.contributor.author Salazar-Lindo, Eduardo
dc.contributor.author Sandhu, Bhupinder
dc.contributor.author Sherman, Philip
dc.contributor.author Shimizu, Toshiaki
dc.contributor.author Guarino, Alfredo
dc.date.accessioned 2019-02-06T14:45:36Z
dc.date.available 2019-02-06T14:45:36Z
dc.date.issued 2016
dc.identifier.uri https://hdl.handle.net/20.500.12866/5104
dc.description.abstract OBJECTIVE: Acute gastroenteritis (AGE) is a major cause of child mortality and morbidity. This study aimed at systematically reviewing clinical practice guidelines (CPGs) on AGE to compare recommendations and provide the basis for developing single universal guidelines. METHODS: CPGs were identified by searching MEDLINE, Cochrane-Library, National Guideline Clearinghouse and Web sites of relevant societies/organizations producing and/or endorsing CPGs. RESULTS: The definition of AGE varies among the 15 CPGs identified. The parameters most frequently recommended to assess dehydration are skin turgor and sunken eyes (11/15, 73.3%), general appearance (11/15, 66.6%), capillary refill time, and mucous membranes appearance (9/15, 60%). Oral rehydration solution is universally recognized as first-line treatment. The majority of CPGs recommend hypo-osmolar (Na 45-60 mmol/L, 11/15, 66.6 %) or low-osmolality (Na 75 mmol/L, 9/15, 60%) solutions. In children who fail oral rehydration, most CPGs suggest intravenous rehydration (66.6%). However, nasogastric tube insertion for fluid administration is preferred according by 5/15 CPGs (33.3%). Changes in diet and withdrawal of food are discouraged by all CPGs, and early refeeding is strongly recommended in 13 of 15 (86.7%). Zinc is recommended as an adjunct to ORS by 10 of 15 (66.6%) CPGs, most of them from low-income countries. Probiotics are considered by 9 of 15 (60%) CPGs, 5 from high-income countries. Antiemetics are not recommended in 9 of 15 (60%) CPGs. Routine use of antibiotics is discouraged. CONCLUSIONS: Key recommendations for the management of AGE in children are similar in CPGs. Together with accurate review of evidence-base this may represent a starting point for developing universal recommendations for the management of children with AGE worldwide. en_US
dc.language.iso eng
dc.publisher Wiley
dc.relation.ispartofseries Journal of Pediatric Gastroenterology and Nutrition
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Practice Guidelines as Topic en_US
dc.subject Acute Disease en_US
dc.subject Child en_US
dc.subject Gastroenteritis/diagnosis/therapy en_US
dc.subject Humans en_US
dc.title Comparison of Recommendations in Clinical Practice Guidelines for Acute Gastroenteritis in Children en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1097/MPG.0000000000001133
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.03
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.19
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.04
dc.relation.issn 1536-4801


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