Universidad Peruana Cayetano Heredia

Kato-Katz and Lumbreras rapid sedimentation test to evaluate helminth prevalence in the setting of a school-based deworming program

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dc.contributor.author Lopez, Martha
dc.contributor.author Morales Fernández, María Luisa
dc.contributor.author Konana, Monisha
dc.contributor.author Hoyer, Paige
dc.contributor.author Pineda-Reyes, Roberto
dc.contributor.author White, Arthur-Clinton-Jr
dc.contributor.author García Lescano, Héctor Hugo
dc.contributor.author Lescano Guevara, Andres Guillermo
dc.contributor.author Gotuzzo Herencia, José Eduardo
dc.contributor.author Cabada, Miguel-Mauricio
dc.date.accessioned 2019-02-06T14:45:37Z
dc.date.available 2019-02-06T14:45:37Z
dc.date.issued 2016
dc.identifier.uri https://hdl.handle.net/20.500.12866/5106
dc.description.abstract The sensitivity of the Kato-Katz test is suboptimal for the evaluation of intestinal helminth prevalence. Moreover, during mass deworming, as helminth egg burden decreases, the sensitivity is likely to decrease. The Lumbreras rapid sedimentation (Lumbreras) is a low-cost non-quantitative test, but may provide useful information in low burden areas. We compared the prevalence of intestinal helminth infections assessed by the Kato-Katz and the Lumbreras rapid sedimentation test on 3 stool specimens from each of 1083 children. The sensitivities were compared using the McNemar paired test. Using the combined outcome of the 3 different stool tests as the standard, Kato-Katz had lower sensitivity than Lumbreras rapid sedimentation tests for Ascaris lumbricoides (85.1% vs. 95.1%, p = 0.03), Hymenolepis nana (77.7% vs. 97.9%, p < 0.01), Trichuris trichura (41.7% vs. 100%, p = 0.01), hookworm (0% vs. 100%, p = 0.01), and Strongyloides stercoralis (0% vs. 88%, p < 0.01). Kato-Katz demonstrated significantly lower sensitivity, missing most T. trichiura, hookworm, and S. stercoralis infections. The combination of Kato-Katz and Lumbreras rapid sedimentation tests enables the detection of more intestinal helminths infections in post-deworming low prevalence areas. en_US
dc.language.iso eng
dc.publisher Taylor and Francis
dc.relation.ispartofseries Pathogens and Global Health
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Clinical Laboratory Techniques en_US
dc.subject School Health Services en_US
dc.subject Animals en_US
dc.subject Ascaris lumbricoides/isolation & purification en_US
dc.subject Child en_US
dc.subject Child, Preschool en_US
dc.subject Feces/parasitology en_US
dc.subject Female en_US
dc.subject Helminthiasis/diagnosis/epidemiology/parasitology en_US
dc.subject Humans en_US
dc.subject Intestinal Diseases, Parasitic/diagnosis/epidemiology/parasitology en_US
dc.subject Kato-Katz en_US
dc.subject Lumbreras rapid sedimentation en_US
dc.subject Male en_US
dc.subject Parasite Egg Count en_US
dc.subject Prevalence en_US
dc.subject Schools en_US
dc.subject Screening tests en_US
dc.subject Sensitivity en_US
dc.subject Sensitivity and Specificity en_US
dc.subject Soil-transmitted helminths en_US
dc.title Kato-Katz and Lumbreras rapid sedimentation test to evaluate helminth prevalence in the setting of a school-based deworming program en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1080/20477724.2016.1187361
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#1.06.01
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.07
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.08
dc.relation.issn 2047-7732


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