Universidad Peruana Cayetano Heredia

Carcinogenesis associated with parasites other than Schistosoma, Opisthorchis and Clonorchis: A systematic review

Mostrar el registro sencillo del ítem

dc.contributor.author Machicado Rivero, Claudia Inés Gloria
dc.contributor.author Marcos, Luis-A.
dc.date.accessioned 2019-02-06T14:45:37Z
dc.date.available 2019-02-06T14:45:37Z
dc.date.issued 2016
dc.identifier.uri https://hdl.handle.net/20.500.12866/5110
dc.description.abstract Only three helminths (Schistosoma haematobium, Opisthorchis viverrini and Clonorchis sinensis) are directly associated with carcinogenesis in humans whereas the role of other parasites in cancer remains unclear. This study aimed to perform a systematic review to identify recent insights in the role of other parasite infections in carcinogenesis. We conducted systematic searches of MEDLINE and EMBASE on July 2015. Our primary outcome was the association between parasitic infections and carcinogenesis. Out of 1,266 studies, 19 were selected for detailed evaluation (eight for helminths and 11 for protozoa). The mechanisms of helminth-induced cancer included chronic inflammation, sustained proliferation, modulation of the host immune system, reprogramming of glucose metabolism and redox signaling, induction of genomic instability and destabilization of suppressor tumor proteins, stimulation of angiogenesis, resisting cell death, and activation of invasion and metastasis. In addition to the current knowledge, the following parasites were found in cancers or tumors: Echinococcus, Strongyloides, Fasciola, Heterakis, Platynosomum and Trichuris. Additional parasites were found in this systematic review that could potentially be associated with cancers or tumors but further evidence is needed to elaborate a cause-effect relationship. en_US
dc.language.iso eng
dc.publisher Wiley
dc.relation.ispartofseries International Journal of Cancer
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Animals en_US
dc.subject carcinogenesis en_US
dc.subject Carcinogenesis en_US
dc.subject Clonorchiasis/complications en_US
dc.subject helminths en_US
dc.subject Humans en_US
dc.subject Neoplasms/metabolism/parasitology/pathology en_US
dc.subject Opisthorchiasis/complications en_US
dc.subject parasite infection en_US
dc.subject protozoa en_US
dc.title Carcinogenesis associated with parasites other than Schistosoma, Opisthorchis and Clonorchis: A systematic review en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1002/ijc.30028
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.21
dc.relation.issn 1097-0215


Ficheros en el ítem

Ficheros Tamaño Formato Ver

No hay ficheros asociados a este ítem.

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem

info:eu-repo/semantics/restrictedAccess Excepto si se señala otra cosa, la licencia del ítem se describe como info:eu-repo/semantics/restrictedAccess

Buscar en el Repositorio


Listar

Panel de Control

Estadísticas