DSpace Repository

Virulence factors profiles and ESBL production in Escherichia coli causing bacteremia in Peruvian children

Show simple item record

dc.contributor.author Palma, Noemi
dc.contributor.author Gomes, Claudia
dc.contributor.author Riveros Ramirez, Maribel Denise
dc.contributor.author Garcia, Wilfredo
dc.contributor.author Martinez-Puchol, Sandra
dc.contributor.author Ruiz-Roldan, Lidia
dc.contributor.author Mateu, Judit
dc.contributor.author García Apac, Coralith Marlinda
dc.contributor.author Jacobs, Jan
dc.contributor.author Ochoa Woodell, Theresa Jean
dc.contributor.author Ruiz, Joaquim
dc.date.accessioned 2019-02-06T14:45:57Z
dc.date.available 2019-02-06T14:45:57Z
dc.date.issued 2016
dc.identifier.uri https://hdl.handle.net/20.500.12866/5134
dc.description.abstract The presence of 25 virulence genes (VGs), genetic phylogroups, quinolone-resistance and Extended Spectrum beta-lactamase (ESBL)-production was assessed in 65 Escherichia coli isolates from blood cultures in children <5 years in Peru. The most frequent VGs were fimA (89.2%), iutA (83.1%), agn43 (72.3%), iucA (67.7%), and fyuA (49.2%). The isolates belonged to D (47.7%), A (26.1%), B1 (21.5%), and B2 (4.6%) phylogroups. D + B2 isolates presented a high number of fimA, hly, papC, sat, and fyuA genes. Quinolone-susceptible (22 isolates - 33.8%) and ESBL-negative (31 isolates - 47.7%) isolates carried more VGs that their respective counterparts (5.7 vs. 4.7 and 5.3 vs. 4.4 respectively); the frequency of the fyuA, aat, aap, and hly genes significantly differed between quinolone-resistant and quinolone-susceptible isolates. Neonatal sepsis isolates tended to be more quinolone-resistant (P = 0.0697) and ESBL-producers (P = 0.0776). Early-onset neonatal sepsis isolates possessed a high number of VGs (5.2 VGs), especially in neonates of </=1 day (5.9 VGs). en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries Diagnostic Microbiology and Infectious Disease
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Anti-Bacterial Agents/pharmacology en_US
dc.subject Bacteremia en_US
dc.subject Bacteremia/microbiology en_US
dc.subject beta-Lactamases/metabolism en_US
dc.subject Blood/microbiology en_US
dc.subject Child, Preschool en_US
dc.subject Drug Resistance, Bacterial en_US
dc.subject ESBL en_US
dc.subject Escherichia coli Infections/microbiology en_US
dc.subject Escherichia coli/classification/enzymology/isolation & purification/pathogenicity en_US
dc.subject Extra-intestinal Escherichia coli en_US
dc.subject Female en_US
dc.subject Genotype en_US
dc.subject Humans en_US
dc.subject Infant en_US
dc.subject Infant, Newborn en_US
dc.subject Male en_US
dc.subject Neonatal sepsis en_US
dc.subject Peru en_US
dc.subject Quinolone-resistance en_US
dc.subject Quinolones/pharmacology en_US
dc.subject Virulence en_US
dc.subject Virulence Factors/analysis/genetics en_US
dc.title Virulence factors profiles and ESBL production in Escherichia coli causing bacteremia in Peruvian children en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1016/j.diagmicrobio.2016.05.017
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.08
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#1.06.01
dc.relation.issn 1879-0070


Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

info:eu-repo/semantics/restrictedAccess Except where otherwise noted, this item's license is described as info:eu-repo/semantics/restrictedAccess

Search DSpace


Browse

My Account

Statistics