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Obesity and its Relation With Diabetes and Hypertension: A Cross-Sectional Study Across 4 Geographical Regions

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dc.contributor.author Patel, Shivani-A.
dc.contributor.author Ali, Mohammed-K.
dc.contributor.author Alam, Dewan
dc.contributor.author Yan, Lijing-L.
dc.contributor.author Levitt, Naomi-S.
dc.contributor.author Bernabé Ortiz, Antonio
dc.contributor.author Checkley, William
dc.contributor.author Wu, Yangfeng
dc.contributor.author Irazola, Vilma
dc.contributor.author Gutierrez, Laura
dc.contributor.author Rubinstein, Adolfo
dc.contributor.author Shivashankar, Roopa
dc.contributor.author Li, Xian
dc.contributor.author Miranda, J. Jaime
dc.contributor.author Chowdhury, Muhammad-Ashique-Haider
dc.contributor.author Siddiquee, Ali-Tanweer
dc.contributor.author Gaziano, Thomas-A.
dc.contributor.author Kadir, M. Masood
dc.contributor.author Prabhakaran, Dorairaj
dc.date.accessioned 2019-02-06T14:45:57Z
dc.date.available 2019-02-06T14:45:57Z
dc.date.issued 2016
dc.identifier.uri https://hdl.handle.net/20.500.12866/5138
dc.description.abstract BACKGROUND: The implications of rising obesity for cardiovascular health in middle-income countries has generated interest, in part because associations between obesity and cardiovascular health seem to vary across ethnic groups. OBJECTIVE: We assessed general and central obesity in Africa, East Asia, South America, and South Asia. We further investigated whether body mass index (BMI) and waist circumference differentially relate to cardiovascular health; and associations between obesity metrics and adverse cardiovascular health vary by region. METHODS: Using baseline anthropometric data collected between 2008 and 2012 from 7 cohorts in 9 countries, we estimated the proportion of participants with general and central obesity using BMI and waist circumference classifications, respectively, by study site. We used Poisson regression to examine the associations (prevalence ratios) of continuously measured BMI and waist circumference with prevalent diabetes and hypertension by sex. Pooled estimates across studies were computed by sex and age. RESULTS: This study analyzed data from 31,118 participants aged 20 to 79 years. General obesity was highest in South Asian cities and central obesity was highest in South America. The proportion classified with general obesity (range 11% to 50%) tended to be lower than the proportion classified as centrally obese (range 19% to 79%). Every standard deviation higher of BMI was associated with 1.65 and 1.60 times higher probability of diabetes and 1.42 and 1.28 times higher probability of hypertension, for men and women, respectively, aged 40 to 69 years. Every standard deviation higher of waist circumference was associated with 1.48 and 1.74 times higher probability of diabetes and 1.34 and 1.31 times higher probability of hypertension, for men and women, respectively, aged 40 to 69 years. Associations of obesity measures with diabetes were strongest in South Africa among men and in South America among women. Associations with hypertension were weakest in South Africa among both sexes. CONCLUSIONS: BMI and waist circumference were both reasonable predictors of prevalent diabetes and hypertension. Across diverse ethnicities and settings, BMI and waist circumference remain salient metrics of obesity that can identify those with increased cardiovascular risk. en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries Global Heart
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Adult en_US
dc.subject Aged en_US
dc.subject Argentina/epidemiology en_US
dc.subject Bangladesh/epidemiology en_US
dc.subject Body Mass Index en_US
dc.subject Chile/epidemiology en_US
dc.subject China/epidemiology en_US
dc.subject Cohort Studies en_US
dc.subject Cross-Sectional Studies en_US
dc.subject Diabetes Mellitus/epidemiology en_US
dc.subject Female en_US
dc.subject Humans en_US
dc.subject Hypertension/epidemiology en_US
dc.subject India/epidemiology en_US
dc.subject Male en_US
dc.subject Middle Aged en_US
dc.subject Obesity, Abdominal/epidemiology en_US
dc.subject Obesity/epidemiology en_US
dc.subject Pakistan/epidemiology en_US
dc.subject Peru/epidemiology en_US
dc.subject Prevalence en_US
dc.subject South Africa/epidemiology en_US
dc.subject Uruguay/epidemiology en_US
dc.subject Waist Circumference en_US
dc.subject Young Adult en_US
dc.title Obesity and its Relation With Diabetes and Hypertension: A Cross-Sectional Study Across 4 Geographical Regions en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1016/j.gheart.2016.01.003
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.04
dc.relation.issn 2211-8179


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