Universidad Peruana Cayetano Heredia

Chronic Mountain Sickness: Clinical Aspects, Etiology, Management, and Treatment

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dc.contributor.author Villafuerte, Francisco C.
dc.contributor.author Corante, Noemi
dc.date.accessioned 2019-02-06T14:48:07Z
dc.date.available 2019-02-06T14:48:07Z
dc.date.issued 2016
dc.identifier.uri https://hdl.handle.net/20.500.12866/5175
dc.description.abstract Villafuerte, Francisco C., and Noemi Corante. Chronic mountain sickness: clinical aspects, etiology, management, and treatment. High Alt Med Biol. 17:61-69, 2016.-Millions of people worldwide live at a high altitude, and a significant number are at risk of developing Chronic Mountain Sickness (CMS), a progressive incapacitating syndrome caused by lifelong exposure to hypoxia. CMS is characterized by severe symptomatic excessive erythrocytosis (EE; Hb >/=19 g/dL for women and Hb >/=21 g/dL for men) and accentuated hypoxemia, which are frequently associated with pulmonary hypertension. In advanced cases, the condition may evolve to cor pulmonale and congestive heart failure. Current knowledge indicates a genetic predisposition to develop CMS. However, there are important risk factors and comorbidities that may trigger and aggravate the condition. Thus, appropriate medical information on CMS is necessary to provide adequate diagnosis and healthcare to high-altitude inhabitants. After reviewing basic clinical aspects of CMS, including its definition, diagnosis, and common clinical findings, we discuss aspects of its etiology, and address its epidemiology, risk factors, and treatment. en_US
dc.language.iso eng
dc.publisher Mary Ann Liebert
dc.relation.ispartofseries High Altitude Medicine and Biology
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Altitude en_US
dc.subject Altitude Sickness/etiology/pathology/therapy en_US
dc.subject Chronic Disease en_US
dc.subject chronic hypoxia en_US
dc.subject chronic mountain sickness en_US
dc.subject Disease Management en_US
dc.subject excessive erythrocytosis en_US
dc.subject Female en_US
dc.subject Genetic Predisposition to Disease en_US
dc.subject high altitude en_US
dc.subject Humans en_US
dc.subject Hypertension, Pulmonary/etiology en_US
dc.subject Hypoxia/etiology en_US
dc.subject Male en_US
dc.subject Polycythemia/etiology en_US
dc.subject Risk Factors en_US
dc.title Chronic Mountain Sickness: Clinical Aspects, Etiology, Management, and Treatment en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1089/ham.2016.0031
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.01.08
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.11
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.05
dc.relation.issn 1557-8682


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