Universidad Peruana Cayetano Heredia

Characteristics Associated With Antihypertensive Treatment and Blood Pressure Control: A Population-Based Follow-Up Study in Peru

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dc.contributor.author Zavala-Loayza, J. Alfredo
dc.contributor.author Pastorius-Benziger, Catherine
dc.contributor.author Cárdenas García-Santillán, María Kathia
dc.contributor.author Carrillo Larco, Rodrigo Martín
dc.contributor.author Bernabé Ortiz, Antonio
dc.contributor.author Gilman, Robert Hugh
dc.contributor.author Checkley, William
dc.contributor.author Miranda, J. Jaime
dc.date.accessioned 2019-02-06T14:48:08Z
dc.date.available 2019-02-06T14:48:08Z
dc.date.issued 2016
dc.identifier.uri https://hdl.handle.net/20.500.12866/5181
dc.description.abstract BACKGROUND: Over one-quarter of the world's adult population has hypertension, yet achieving adequate treatment or control targets remains a challenge. OBJECTIVE: This study sought to identify, longitudinally, characteristics associated with antihypertensive treatment and blood pressure (BP) control among individuals with hypertension. METHODS: Data from individuals enrolled in the population-based CRONICAS Cohort Study (adults >/=35 years, living in 4 different rural/urban and coastal/high-altitude Peruvian settings) with hypertension at baseline were used. Antihypertensive treatment and BP control were assessed at baseline and at 15 months. Multinomial logistic regressions were used to estimate relative risk ratios (RRR) and 95% confidence intervals (95% CI) of factors associated with antihypertensive treatment and BP control at follow-up. RESULTS: At baseline, among 717 individuals with hypertension (53% women, mean age 61.5 +/- 12.4 years), 28% were unaware of their hypertension status, 30% were aware but untreated, 16% were treated but uncontrolled, and 26% were treated and controlled. At follow-up, 89% of unaware and 82% of untreated individuals persisted untreated, and only 58% of controlled individuals remained controlled. Positive predictors of receiving treatment and being controlled at follow-up included age (RRR: 0.81; 95% CI: 0.73 to 0.91 for every 5 years) and family history of a chronic disease (RRR: 0.53; 95% CI: 0.31 to 0.92 vs. no history); whereas Puno rural site (RRR: 16.51; 95% CI: 1.90 to 143.56 vs. Lima) and male sex (RRR: 2.59; 95% CI: 1.54 to 4.36) were risk factors. Systolic BP at baseline (RRR: 1.27; 95% CI: 1.16 to 1.39 for every 5 mm Hg) and male sex (RRR: 1.75, 95% CI: 1.02 to 2.98) were risk factors for being treated but uncontrolled at follow-up. CONCLUSIONS: Large gaps in treatment of hypertension were observed. Targeting specific populations such as men, younger individuals, or those without family history of disease may increase coverage of antihypertensive treatment. Also, targeting male individuals or those with higher systolic BP could yield better rates of BP control in the short term. en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries Global Heart
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Blood Pressure en_US
dc.subject Health Knowledge, Attitudes, Practice en_US
dc.subject Adult en_US
dc.subject Age Factors en_US
dc.subject Aged en_US
dc.subject Antihypertensive Agents/therapeutic use en_US
dc.subject Female en_US
dc.subject Follow-Up Studies en_US
dc.subject Humans en_US
dc.subject Hypertension/drug therapy en_US
dc.subject Logistic Models en_US
dc.subject Longitudinal Studies en_US
dc.subject Male en_US
dc.subject Middle Aged en_US
dc.subject Peru en_US
dc.subject Risk Factors en_US
dc.subject Rural Population en_US
dc.subject Sex Factors en_US
dc.title Characteristics Associated With Antihypertensive Treatment and Blood Pressure Control: A Population-Based Follow-Up Study in Peru en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1016/j.gheart.2015.12.002
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.04
dc.relation.issn 2211-8179


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