Universidad Peruana Cayetano Heredia

Treponema pallidum pallidum Genotypes and Macrolide Resistance Status in Syphilitic Lesions among Patients at 2 Sexually Transmitted Infection Clinics in Lima, Peru

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dc.contributor.author Flores, Juan-Antonio
dc.contributor.author Vargas Rivera, Silver Keith
dc.contributor.author León Sandoval, Segundo Ramos
dc.contributor.author Perez, Danny-Giancarlo
dc.contributor.author Ramos, Lourdes-Beatriz
dc.contributor.author Chow, Jeremy
dc.contributor.author Konda, Kelika-Anne
dc.contributor.author Calvo, Gino-Mauricio
dc.contributor.author Salvatierra, Hector-J.
dc.contributor.author Klausner, Jeffrey-D.
dc.contributor.author Caceres Palacios, Carlos Fernando
dc.date.accessioned 2019-02-06T14:51:19Z
dc.date.available 2019-02-06T14:51:19Z
dc.date.issued 2016
dc.identifier.uri https://hdl.handle.net/20.500.12866/5209
dc.description.abstract We report the circulating genotypes and the frequency of macrolide-resistance patterns among Treponema pallidum pallidum DNA isolated from syphilitic lesions from patients who attended 2 sexual health clinics in Lima, Peru. We implemented and used a molecular typing scheme to describe local T. pallidum pallidum strains. Among 14 specimens, subtype 14d/f was the most prevalent strain in 7 fully typed T. pallidum DNA specimens obtained from men who have sex with men and transgender women presenting with chancre-like lesions. No macrolide-resistance mutations were found in T. pallidum DNA from 10 lesions. en_US
dc.language.iso eng
dc.publisher Wolters Kluwer Health
dc.relation.ispartofseries Sexually Transmitted Diseases
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Drug Resistance, Bacterial en_US
dc.subject Female en_US
dc.subject Genotype en_US
dc.subject Homosexuality, Male en_US
dc.subject Humans en_US
dc.subject Macrolides/pharmacology en_US
dc.subject Male en_US
dc.subject Molecular Typing en_US
dc.subject Mutation en_US
dc.subject Peru/epidemiology en_US
dc.subject Sexually Transmitted Diseases, Bacterial/drug therapy/epidemiology/microbiology en_US
dc.subject Syphilis/drug therapy/epidemiology/microbiology en_US
dc.subject Transgender Persons en_US
dc.subject Treponema pallidum/classification/drug effects/genetics en_US
dc.title Treponema pallidum pallidum Genotypes and Macrolide Resistance Status in Syphilitic Lesions among Patients at 2 Sexually Transmitted Infection Clinics in Lima, Peru en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1097/OLQ.0000000000000465
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.15
dc.relation.issn 1537-4521


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