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Enteric Fever: A Slow Response to an Old Plague

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dc.contributor.author Franco-Paredes, Carlos
dc.contributor.author Khan, M. Imran
dc.contributor.author Gonzalez-Diaz, Esteban
dc.contributor.author Santos-Preciado, Jose-I.
dc.contributor.author Rodriguez-Morales, Alfonso-J.
dc.contributor.author Gotuzzo Herencia, José Eduardo
dc.date.accessioned 2019-02-06T14:51:19Z
dc.date.available 2019-02-06T14:51:19Z
dc.date.issued 2016
dc.identifier.uri https://hdl.handle.net/20.500.12866/5211
dc.description.abstract Man is irremediably embedded in nature with complex interactions with all living organisms. Historically, the establishment of contemporary human societies has been influenced by our coexistence with other microorganisms living in highly interconnected habitats and ecologies. As a result, with the progression from unicellular to multicellular life, bacteria have coexisted with humans. In this biological journey, while there are important benefits provided by bacterial guests to the human host living in complex relationships and becoming part of their microbiome, some organisms are able to cause a wide spectrum of diseases. Among the large Enterobacteriaceae family, the genus Salmonella, a pathotype of Escherichia coli, is one example. Salmonella is further classified into S. enterica and S. bongori serotypes based on its lipopolysaccharide cell wall (somatic O antigen), its flagellar (H antigen), and its surface Vi antigen (present only in S. typhi, S. Paratyphi C, Citrobacter freundii, and S. Dublin). S. enterica subspecies I, one of the six subspecies of S. enterica, is a major contributor to human disease (Fig 1). This group of pathogens includes those frequently causing gastroenteritis, such as S. Typhimurium, those causing invasive disease in the forms of bacteremia, such as S. Choleraesius, or the typhoidal Salmonella species causing enteric fever, including S. typhi (typhoid fever) and S. Paratyphi A, B, and C (paratyphoid fever)... en_US
dc.language.iso eng
dc.publisher Public Library of Science
dc.relation.ispartofseries PLoS Neglected Tropical Diseases
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Cost of Illness en_US
dc.subject Humans en_US
dc.subject Paratyphoid Fever/economics/prevention & control en_US
dc.subject Typhoid Fever/economics/prevention & control en_US
dc.title Enteric Fever: A Slow Response to an Old Plague en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1371/journal.pntd.0004597
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn 1935-2735


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