Enteric Fever: A Slow Response to an Old Plague

Franco-Paredes, Carlos; Gonzalez-Diaz, Esteban; Rodriguez-Morales, Alfonso-J.; Gotuzzo Herencia, José Eduardo; Santos-Preciado, Jose-I.; Khan, M. Imran

dc.contributor.author	Franco-Paredes, Carlos
dc.contributor.author	Khan, M. Imran
dc.contributor.author	Gonzalez-Diaz, Esteban
dc.contributor.author	Santos-Preciado, Jose-I.
dc.contributor.author	Rodriguez-Morales, Alfonso-J.
dc.contributor.author	Gotuzzo Herencia, José Eduardo
dc.date.accessioned	2019-02-06T14:51:19Z
dc.date.available	2019-02-06T14:51:19Z
dc.date.issued	2016
dc.identifier.uri	https://hdl.handle.net/20.500.12866/5211
dc.description.abstract	Man is irremediably embedded in nature with complex interactions with all living organisms. Historically, the establishment of contemporary human societies has been influenced by our coexistence with other microorganisms living in highly interconnected habitats and ecologies. As a result, with the progression from unicellular to multicellular life, bacteria have coexisted with humans. In this biological journey, while there are important benefits provided by bacterial guests to the human host living in complex relationships and becoming part of their microbiome, some organisms are able to cause a wide spectrum of diseases. Among the large Enterobacteriaceae family, the genus Salmonella, a pathotype of Escherichia coli, is one example. Salmonella is further classified into S. enterica and S. bongori serotypes based on its lipopolysaccharide cell wall (somatic O antigen), its flagellar (H antigen), and its surface Vi antigen (present only in S. typhi, S. Paratyphi C, Citrobacter freundii, and S. Dublin). S. enterica subspecies I, one of the six subspecies of S. enterica, is a major contributor to human disease (Fig 1). This group of pathogens includes those frequently causing gastroenteritis, such as S. Typhimurium, those causing invasive disease in the forms of bacteremia, such as S. Choleraesius, or the typhoidal Salmonella species causing enteric fever, including S. typhi (typhoid fever) and S. Paratyphi A, B, and C (paratyphoid fever)...	en_US
dc.language.iso	eng
dc.publisher	Public Library of Science
dc.relation.ispartofseries	PLoS Neglected Tropical Diseases
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject	Cost of Illness	en_US
dc.subject	Humans	en_US
dc.subject	Paratyphoid Fever/economics/prevention & control	en_US
dc.subject	Typhoid Fever/economics/prevention & control	en_US
dc.title	Enteric Fever: A Slow Response to an Old Plague	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.1371/journal.pntd.0004597
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn	1935-2735