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A scoping review of cost-effectiveness of screening and treatment for latent tubercolosis infection in migrants from high-incidence countries

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dc.contributor.author Zammarchi, Lorenzo
dc.contributor.author Casadei, Gianluigi
dc.contributor.author Strohmeyer, Marianne
dc.contributor.author Bartalesi, Filippo
dc.contributor.author Liendo, Carola
dc.contributor.author Matteelli, Alberto
dc.contributor.author Bonati, Maurizio
dc.contributor.author Gotuzzo Herencia, José Eduardo
dc.contributor.author Bartoloni, Alessandro
dc.date.accessioned 2019-02-06T14:52:14Z
dc.date.available 2019-02-06T14:52:14Z
dc.date.issued 2015
dc.identifier.uri https://hdl.handle.net/20.500.12866/5283
dc.description.abstract BACKGROUND: In low-incidence countries, most tuberculosis (TB) cases occur among migrants and are caused by reactivation of latent tuberculosis infection (LTBI) acquired in the country of origin. Diagnosis and treatment of LTBI are rarely implemented to reduce the burden of TB in immigrants, partly because the cost-effectiveness profile of this intervention is uncertain. The objective of this research is to perform a review of the literature to assess the cost-effectiveness of LTBI diagnosis and treatment strategies in migrants. METHODS: Scoping review of economic evaluations on LTBI screening strategies for migrants was carried out in Medline. RESULTS: Nine studies met the inclusion criteria. LTBI screening was cost-effective according to seven studies. Findings of four studies support interferon gamma release assay as the most cost-effective test for LTBI screening in migrants. Two studies found that LTBI screening is cost-effective only if carried out in immigrants who are contacts of active TB cases. DISCUSSION AND CONCLUSIONS: Our findings support the cost-effectiveness of LTBI diagnostic and treatment strategies in migrants especially if they are focused on young subjects from high incidence countries. These strategies could represent and adjunctive and synergistic tool to achieve the ambitious aim of TB elimination. en_US
dc.language.iso eng
dc.publisher BioMed Central
dc.relation.ispartofseries BMC Health Services Research
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Female en_US
dc.subject Humans en_US
dc.subject Male en_US
dc.subject Communicable Diseases en_US
dc.subject Incidence en_US
dc.subject Cost-Benefit Analysis en_US
dc.subject Transients and Migrants en_US
dc.subject Dental Care en_US
dc.subject Interferon-gamma Release Tests/economics en_US
dc.subject Latent Tuberculosis/diagnosis/drug therapy en_US
dc.subject Mass Screening/economics en_US
dc.subject Tuberculin Test/economics en_US
dc.subject Tuberculosis/epidemiology en_US
dc.title A scoping review of cost-effectiveness of screening and treatment for latent tubercolosis infection in migrants from high-incidence countries en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1186/s12913-015-1045-3
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.02
dc.relation.issn 1472-6963

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