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Burden of chronic kidney disease in resource-limited settings from Peru: a population-based study

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dc.contributor.author Francis, Elizabeth R.
dc.contributor.author Kuo, Chin-Chi
dc.contributor.author Bernabé Ortiz, Antonio
dc.contributor.author Nessel, Lisa
dc.contributor.author Gilman, Robert Hugh
dc.contributor.author Checkley, William
dc.contributor.author Miranda, J. Jaime
dc.contributor.author Feldman, Harold I.
dc.date.accessioned 2019-02-06T14:52:15Z
dc.date.available 2019-02-06T14:52:15Z
dc.date.issued 2015
dc.identifier.uri https://hdl.handle.net/20.500.12866/5286
dc.description.abstract BACKGROUND: The silent progression of chronic kidney diseases (CKD) and its association with other chronic diseases, and high treatment costs make it a great public health concern worldwide. The population burden of CKD in Peru has yet to be fully described. METHODS: We completed a cross sectional study of CKD prevalence among 404 participants (total study population median age 54.8 years, 50.2 % male) from two sites, highly-urbanized Lima and less urbanized Tumbes, who were enrolled in the population-based CRONICAS Cohort Study of cardiopulmonary health in Peru. Factors potentially associated with the presence of CKD were explored using Poisson regression, a statistical methodology used to determine prevalence ratios. RESULTS: In total, 68 participants (16.8 %, 95 % CI 13.5-20.9 %) met criteria for CKD: 60 (14.9%) with proteinuria, four (1%) with eGFR < 60 mL/min/1.73 m2 , and four (1%) with both. CKD prevalence was higher in Lima (20.7 %, 95 % CI 15.8-27.1) than Tumbes (12.9 %, 95 % CI 9.0-18.5). Among participants with CKD, the prevalence of diabetes and hypertension was 19.1 % and 42.7 %, respectively. After multivariable adjustment, CKD was associated with older age, female sex, greater wealth tertile (although all wealth strata were below the poverty line), residence in Lima, and presence of diabetes and hypertension. CONCLUSIONS: The high prevalence rates of CKD identified in Lima and Tumbes are similar to estimates from high-income settings. These findings highlight the need to identify occult CKD and implement strategies to prevent disease progression and secondary morbidity. en_US
dc.language.iso eng
dc.publisher BioMed Central
dc.relation.ispartofseries BMC Nephrology
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Adult en_US
dc.subject Female en_US
dc.subject Humans en_US
dc.subject Male en_US
dc.subject Cross-Sectional Studies en_US
dc.subject Aged en_US
dc.subject Middle Aged en_US
dc.subject Peru/epidemiology en_US
dc.subject Prevalence en_US
dc.subject Urban Population/statistics & numerical data en_US
dc.subject Diabetes Mellitus/epidemiology en_US
dc.subject Hypertension/epidemiology en_US
dc.subject Dyslipidemias/epidemiology en_US
dc.subject Health Resources/supply & distribution en_US
dc.subject Proteinuria/epidemiology en_US
dc.subject Renal Insufficiency, Chronic/epidemiology en_US
dc.title Burden of chronic kidney disease in resource-limited settings from Peru: a population-based study en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1186/s12882-015-0104-7
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.20
dc.relation.issn 1471-2369


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