Universidad Peruana Cayetano Heredia

Contribution of modifiable risk factors for hypertension and type-2 diabetes in Peruvian resource-limited settings

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dc.contributor.author Bernabé Ortiz, Antonio
dc.contributor.author Carrillo Larco, Rodrigo Martín
dc.contributor.author Gilman, Robert Hugh
dc.contributor.author Checkley, William
dc.contributor.author Smeeth, Liam
dc.contributor.author Miranda, J. Jaime
dc.contributor.author CRONICAS Cohort Study Group
dc.date.accessioned 2019-02-06T14:52:39Z
dc.date.available 2019-02-06T14:52:39Z
dc.date.issued 2015
dc.identifier.uri https://hdl.handle.net/20.500.12866/5347
dc.description.abstract BACKGROUND: It is important to understand the local burden of non-communicable diseases including within-country heterogeneity. The aim of this study was to characterise hypertension and type-2 diabetes profiles across different Peruvian geographical settings emphasising the assessment of modifiable risk factors. METHODS: Analysis of the CRONICAS Cohort Study baseline assessment was conducted. Cardiometabolic outcomes were blood pressure categories (hypertension, prehypertension, normal) and glucose metabolism disorder status (diabetes, prediabetes, normal). Exposures were study setting and six modifiable factors (smoking, alcohol drinking, leisure time and transport-related physical activity levels, TV watching, fruit/vegetables intake and obesity). Poisson regression models were used to report prevalence ratios (PR). Population attributable risks (PAR) were also estimated. RESULTS: Data from 3238 participants, 48.3% male, mean age 45.3 years, were analysed. Age-standardised (WHO population) prevalence of prehypertension and hypertension was 24% and 16%, whereas for prediabetes and type-2 diabetes it was 18% and 6%, respectively. Outcomes varied according to study setting (p<0.001). In multivariable model, hypertension was higher among daily smokers (PR 1.76), heavy alcohol drinkers (PR 1.61) and the obese (PR 2.06); whereas only obesity (PR 2.26) increased the prevalence of diabetes. PAR showed that obesity was an important determinant for hypertension (15.7%) and type-2 diabetes (23.9%). CONCLUSIONS: There is an evident heterogeneity in the prevalence of and risk factors for hypertension and diabetes within Peru. Prehypertension and prediabetes are highly prevalent across settings. Our results emphasise the need of understanding the epidemiology of cardiometabolic conditions to appropriately implement interventions to tackle the burden of non-communicable diseases. en_US
dc.language.iso eng
dc.publisher BMJ Publishing Group
dc.relation.ispartofseries Journal of Epidemiology and Community Health
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Adult en_US
dc.subject Female en_US
dc.subject Humans en_US
dc.subject Male en_US
dc.subject Cohort Studies en_US
dc.subject Cross-Sectional Studies en_US
dc.subject Surveys and Questionnaires en_US
dc.subject Aged en_US
dc.subject Middle Aged en_US
dc.subject Peru/epidemiology en_US
dc.subject Prevalence en_US
dc.subject Risk Factors en_US
dc.subject Multivariate Analysis en_US
dc.subject Poverty Areas en_US
dc.subject DIABETES en_US
dc.subject Diabetes Mellitus, Type 2/epidemiology/etiology en_US
dc.subject Epidemiology of chronic non communicable diseases en_US
dc.subject HYPERTENSION en_US
dc.subject Hypertension/epidemiology/etiology en_US
dc.title Contribution of modifiable risk factors for hypertension and type-2 diabetes in Peruvian resource-limited settings en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1136/jech-2015-205988
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.09
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.05
dc.relation.issn 1470-2738


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