Public transportation and tuberculosis transmission in a high incidence setting

Ciampi, Antonio; Shah, Lena; Gotuzzo Herencia, José Eduardo; Seas Ramos, Carlos Rafael; Heymann, Jody; Brewer, Timothy F.; Zamudio Fuertes, Carlos Eduardo; Choi, Howard W.; Krapp, Fiorella

dc.contributor.author	Zamudio Fuertes, Carlos Eduardo
dc.contributor.author	Krapp, Fiorella
dc.contributor.author	Choi, Howard W.
dc.contributor.author	Shah, Lena
dc.contributor.author	Ciampi, Antonio
dc.contributor.author	Gotuzzo Herencia, José Eduardo
dc.contributor.author	Heymann, Jody
dc.contributor.author	Seas Ramos, Carlos Rafael
dc.contributor.author	Brewer, Timothy F.
dc.date.accessioned	2019-02-06T14:53:12Z
dc.date.available	2019-02-06T14:53:12Z
dc.date.issued	2015
dc.identifier.uri	https://hdl.handle.net/20.500.12866/5402
dc.description.abstract	BACKGROUND: Tuberculosis (TB) transmission may occur with exposure to an infectious contact often in the setting of household environments, but extra-domiciliary transmission also may happen. We evaluated if using buses and/or minibuses as public transportation was associated with acquiring TB in a high incidence urban district in Lima, Peru. METHODS: Newly diagnosed TB cases with no history of previous treatment and community controls were recruited from August to December 2008 for a case-control study. Crude and adjusted odd ratios (OR) and 95% confidence intervals (CI) were calculated using logistic regression to study the association between bus/minibus use and TB risk. RESULTS: One hundred forty TB cases and 80 controls were included. The overall use of buses/minibuses was 44.9%; 53.3% (72/135) among cases and 30.4% (24/79) among controls [OR: 3.50, (95% CI: 1.60-7.64)]. In the TB group, 25.7% (36/140) of subjects reported having had a recent household TB contact, and 13% (18/139) reported having had a workplace TB contact; corresponding figures for controls were 3.8% (3/80) and 4.1% (3/73), respectively[OR: 8.88 (95% CI: 2.64-29.92), and OR: 3.89 (95% CI: 1.10-13.70)]. In multivariate analyses, age, household income, household contact and using buses/minibuses to commute to work were independently associated with TB [OR for bus/minibus use: 11.8 (95% CI: 1.45-96.07)]. CONCLUSIONS: Bus/minibus use to commute to work is associated with TB risk in this high-incidence, urban population in Lima, Peru. Measures should be implemented to prevent TB transmission through this exposure.	en_US
dc.language.iso	eng
dc.publisher	Public Library of Science
dc.relation.ispartofseries	PLoS ONE
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject	Adult	en_US
dc.subject	Female	en_US
dc.subject	Humans	en_US
dc.subject	Male	en_US
dc.subject	Young Adult	en_US
dc.subject	Middle Aged	en_US
dc.subject	Peru/epidemiology	en_US
dc.subject	Case-Control Studies	en_US
dc.subject	Urban Population	en_US
dc.subject	Transportation	en_US
dc.subject	Incidence	en_US
dc.subject	Tuberculosis/epidemiology/transmission	en_US
dc.title	Public transportation and tuberculosis transmission in a high incidence setting	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.1371/journal.pone.0115230
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.02.07
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.09
dc.relation.issn	1932-6203