Universidad Peruana Cayetano Heredia
Prevalence of chronic obstructive pulmonary disease and variation in risk factors across four geographically diverse resource-limited settings in Peru
JavaScript is disabled for your browser. Some features of this site may not work without it.
Mostrar el registro sencillo del ítem
| dc.contributor.author | Jaganath, Devan | |
| dc.contributor.author | Miranda, J. Jaime | |
| dc.contributor.author | Gilman, Robert Hugh | |
| dc.contributor.author | Wise, Robert A. | |
| dc.contributor.author | Diette, Gregory B. | |
| dc.contributor.author | Miele, Catherine H. | |
| dc.contributor.author | Bernabé Ortiz, Antonio | |
| dc.contributor.author | Checkley, William | |
| dc.date.accessioned | 2019-02-06T14:53:35Z | |
| dc.date.available | 2019-02-06T14:53:35Z | |
| dc.date.issued | 2015 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12866/5411 | |
| dc.description.abstract | BACKGROUND: It is unclear how geographic and social diversity affects the prevalence of chronic obstructive pulmonary disease (COPD). We sought to characterize the prevalence of COPD and identify risk factors across four settings in Peru with varying degrees of urbanization, altitude, and biomass fuel use. METHODS: We collected sociodemographics, clinical history, and post-bronchodilator spirometry in a randomly selected, age-, sex- and site-stratified, population-based sample of 2,957 adults aged >/=35 years (median age was 54.8 years and 49.3% were men) from four resource-poor settings: Lima, Tumbes, urban and rural Puno. We defined COPD as a post-bronchodilator FEV1/FVC < 70%. RESULTS: Overall prevalence of COPD was 6.0% (95% CI 5.1%-6.8%) but with marked variation across sites: 3.6% in semi-urban Tumbes, 6.1% in urban Puno, 6.2% in Lima, and 9.9% in rural Puno (p < 0.001). Population attributable risks (PARs) of COPD due to smoking >/=10 pack-years were less than 10% for all sites, consistent with a low prevalence of daily smoking (3.3%). Rather, we found that PARs of COPD varied by setting. In Lima, for example, the highest PARs were attributed to post-treatment tuberculosis (16% and 22% for men and women, respectively). In rural Puno, daily biomass fuel for cooking among women was associated with COPD (prevalence ratio 2.22, 95% CI 1.02-4.81) and the PAR of COPD due to daily exposure to biomass fuel smoke was 55%. CONCLUSIONS: The burden of COPD in Peru was not uniform and, unlike other settings, was not predominantly explained by tobacco smoking. This study emphasizes the role of biomass fuel use, and highlights pulmonary tuberculosis as an often neglected risk factor in endemic areas. | en_US |
| dc.language.iso | eng | |
| dc.publisher | BioMed Central | |
| dc.relation.ispartofseries | Respiratory Research | |
| dc.rights | info:eu-repo/semantics/restrictedAccess | |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
| dc.subject | Adult | en_US |
| dc.subject | Female | en_US |
| dc.subject | Humans | en_US |
| dc.subject | Male | en_US |
| dc.subject | Urbanization | en_US |
| dc.subject | Aged | en_US |
| dc.subject | Middle Aged | en_US |
| dc.subject | Peru/epidemiology | en_US |
| dc.subject | Altitude | en_US |
| dc.subject | Prevalence | en_US |
| dc.subject | Risk Factors | en_US |
| dc.subject | Longitudinal Studies | en_US |
| dc.subject | Risk Assessment | en_US |
| dc.subject | Urban Health | en_US |
| dc.subject | Rural Health | en_US |
| dc.subject | Biomass | en_US |
| dc.subject | Residence Characteristics | en_US |
| dc.subject | Predictive Value of Tests | en_US |
| dc.subject | Smoking/adverse effects/epidemiology | en_US |
| dc.subject | Spirometry | en_US |
| dc.subject | Forced Expiratory Volume | en_US |
| dc.subject | Fossil Fuels | en_US |
| dc.subject | Lung/physiopathology | en_US |
| dc.subject | Pulmonary Disease, Chronic Obstructive/diagnosis/epidemiology/physiopathology | en_US |
| dc.subject | Tuberculosis, Pulmonary/diagnosis/epidemiology | en_US |
| dc.subject | Vital Capacity | en_US |
| dc.title | Prevalence of chronic obstructive pulmonary disease and variation in risk factors across four geographically diverse resource-limited settings in Peru | en_US |
| dc.type | info:eu-repo/semantics/article | |
| dc.identifier.doi | https://doi.org/10.1186/s12931-015-0198-2 | |
| dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.02.07 | |
| dc.relation.issn | 1465-993X |
Ficheros en el ítem
| Ficheros | Tamaño | Formato | Ver |
|---|---|---|---|
|
No hay ficheros asociados a este ítem. |
|||
Este ítem aparece en la(s) siguiente(s) colección(ones)
-
Artículos en revistas indizadas [4988]
Recuperados de bases de datos bibliográficas
Excepto si se señala otra cosa, la licencia del ítem se describe como info:eu-repo/semantics/restrictedAccess
