Characteristics of Travel-Related Severe Plasmodium vivax and Plasmodium falciparum Malaria in Individuals Hospitalized at a Tertiary Referral Center in Lima, Peru

Vinetz, Joseph Michael; Llanos-Chea, Fiorella; Samalvides Cuba, Frine; Llanos Cuentas, Elmer Alejandro; Rosas, Angel; Martinez, Dalila

dc.contributor.author	Llanos-Chea, Fiorella
dc.contributor.author	Martinez, Dalila
dc.contributor.author	Rosas, Angel
dc.contributor.author	Samalvides Cuba, Frine
dc.contributor.author	Vinetz, Joseph Michael
dc.contributor.author	Llanos Cuentas, Elmer Alejandro
dc.date.accessioned	2019-02-06T14:57:37Z
dc.date.available	2019-02-06T14:57:37Z
dc.date.issued	2015
dc.identifier.uri	https://hdl.handle.net/20.500.12866/5464
dc.description.abstract	Severe Plasmodium falciparum malaria is uncommon in South America. Lima, Peru, while not endemic for malaria, is home to specialized centers for infectious diseases that admit and manage patients with severe malaria (SM), all of whom contracted infection during travel. This retrospective study describes severe travel-related malaria in individuals admitted to one tertiary care referral hospital in Lima, Peru; severity was classified based on criteria published by the World Health Organization in 2000. Data were abstracted from medical records of patients with SM admitted to Hospital Nacional Cayetano Heredia from 2006 to 2011. Of 33 SM cases with complete clinical data, the mean age was 39 years and the male/female ratio was 2.8. Most cases were contracted in known endemic regions within Peru: Amazonia (47%), the central jungle (18%), and the northern coast (12%); cases were also found in five (15%) travelers returning from Africa. Plasmodium vivax was most commonly identified (71%) among the severe infections, followed by P. falciparum (18%); mixed infections composed 11% of the group. Among the criteria of severity, jaundice was most common (58%), followed by severe thrombocytopenia (47%), hyperpyrexia (32%), and shock (15%). Plasmodium vivax mono-infection predominated as the etiology of SM in cases acquired in Peru.	en_US
dc.language.iso	eng
dc.publisher	American Society of Tropical Medicine and Hygiene
dc.relation.ispartofseries	American Journal of Tropical Medicine and Hygiene (ASTMH Journal)
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	Adolescent	en_US
dc.subject	Adult	en_US
dc.subject	Female	en_US
dc.subject	Humans	en_US
dc.subject	Male	en_US
dc.subject	Retrospective Studies	en_US
dc.subject	Tertiary Care Centers	en_US
dc.subject	Young Adult	en_US
dc.subject	Middle Aged	en_US
dc.subject	Peru/epidemiology	en_US
dc.subject	Pregnancy	en_US
dc.subject	Hospitalization	en_US
dc.subject	Travel	en_US
dc.subject	Acute Disease	en_US
dc.subject	Malaria, Falciparum/epidemiology/etiology/pathology	en_US
dc.subject	Malaria, Vivax/epidemiology/etiology/pathology	en_US
dc.title	Characteristics of Travel-Related Severe Plasmodium vivax and Plasmodium falciparum Malaria in Individuals Hospitalized at a Tertiary Referral Center in Lima, Peru	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.4269/ajtmh.14-0652
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn	1476-1645