Universidad Peruana Cayetano Heredia

Characteristics of Travel-Related Severe Plasmodium vivax and Plasmodium falciparum Malaria in Individuals Hospitalized at a Tertiary Referral Center in Lima, Peru

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dc.contributor.author Llanos-Chea, Fiorella
dc.contributor.author Martinez, Dalila
dc.contributor.author Rosas, Angel
dc.contributor.author Samalvides Cuba, Frine
dc.contributor.author Vinetz, Joseph Michael
dc.contributor.author Llanos Cuentas, Elmer Alejandro
dc.date.accessioned 2019-02-06T14:57:37Z
dc.date.available 2019-02-06T14:57:37Z
dc.date.issued 2015
dc.identifier.uri https://hdl.handle.net/20.500.12866/5464
dc.description.abstract Severe Plasmodium falciparum malaria is uncommon in South America. Lima, Peru, while not endemic for malaria, is home to specialized centers for infectious diseases that admit and manage patients with severe malaria (SM), all of whom contracted infection during travel. This retrospective study describes severe travel-related malaria in individuals admitted to one tertiary care referral hospital in Lima, Peru; severity was classified based on criteria published by the World Health Organization in 2000. Data were abstracted from medical records of patients with SM admitted to Hospital Nacional Cayetano Heredia from 2006 to 2011. Of 33 SM cases with complete clinical data, the mean age was 39 years and the male/female ratio was 2.8. Most cases were contracted in known endemic regions within Peru: Amazonia (47%), the central jungle (18%), and the northern coast (12%); cases were also found in five (15%) travelers returning from Africa. Plasmodium vivax was most commonly identified (71%) among the severe infections, followed by P. falciparum (18%); mixed infections composed 11% of the group. Among the criteria of severity, jaundice was most common (58%), followed by severe thrombocytopenia (47%), hyperpyrexia (32%), and shock (15%). Plasmodium vivax mono-infection predominated as the etiology of SM in cases acquired in Peru. en_US
dc.language.iso eng
dc.publisher American Society of Tropical Medicine and Hygiene
dc.relation.ispartofseries American Journal of Tropical Medicine and Hygiene (ASTMH Journal)
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Adolescent en_US
dc.subject Adult en_US
dc.subject Female en_US
dc.subject Humans en_US
dc.subject Male en_US
dc.subject Retrospective Studies en_US
dc.subject Tertiary Care Centers en_US
dc.subject Young Adult en_US
dc.subject Middle Aged en_US
dc.subject Peru/epidemiology en_US
dc.subject Pregnancy en_US
dc.subject Hospitalization en_US
dc.subject Travel en_US
dc.subject Acute Disease en_US
dc.subject Malaria, Falciparum/epidemiology/etiology/pathology en_US
dc.subject Malaria, Vivax/epidemiology/etiology/pathology en_US
dc.title Characteristics of Travel-Related Severe Plasmodium vivax and Plasmodium falciparum Malaria in Individuals Hospitalized at a Tertiary Referral Center in Lima, Peru en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.4269/ajtmh.14-0652
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn 1476-1645


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