Insecticide Resistance in Areas Under Investigation by the International Centers of Excellence for Malaria Research: A Challenge for Malaria Control and Elimination

Quinones, Martha L.; Keven, John B.; Eapen, Alex; Moreno, Marta; Cooper, Robert; Palomino, Miriam; Conn, Jan E.; Bugoro, Hugo; Donnelly, Martin J.; Kumar, Ashwani; Coulibaly, Mamadou B.; Burkot, Thomas R.; Beier, John C.; Norris, Douglas E.; Montgomery, Jacqui; Mawejje, Henry D.; Rosas, Angel; Yan, Guiyun

dc.contributor.author	Quinones, Martha L.
dc.contributor.author	Norris, Douglas E.
dc.contributor.author	Conn, Jan E.
dc.contributor.author	Moreno, Marta
dc.contributor.author	Burkot, Thomas R.
dc.contributor.author	Bugoro, Hugo
dc.contributor.author	Keven, John B.
dc.contributor.author	Cooper, Robert
dc.contributor.author	Yan, Guiyun
dc.contributor.author	Rosas, Angel
dc.contributor.author	Palomino, Miriam
dc.contributor.author	Donnelly, Martin J.
dc.contributor.author	Mawejje, Henry D.
dc.contributor.author	Eapen, Alex
dc.contributor.author	Montgomery, Jacqui
dc.contributor.author	Coulibaly, Mamadou B.
dc.contributor.author	Beier, John C.
dc.contributor.author	Kumar, Ashwani
dc.date.accessioned	2019-02-06T14:57:38Z
dc.date.available	2019-02-06T14:57:38Z
dc.date.issued	2015
dc.identifier.uri	https://hdl.handle.net/20.500.12866/5468
dc.description.abstract	Scale-up of the main vector control interventions, residual insecticides sprayed on walls or structures and/or impregnated in bed nets, together with prompt diagnosis and effective treatment, have led to a global reduction in malaria transmission. However, resistance in vectors to almost all classes of insecticides, particularly to the synthetic pyrethroids, is posing a challenge to the recent trend of declining malaria. Ten International Centers of Excellence for Malaria Research (ICEMR) located in the most malaria-endemic regions of the world are currently addressing insecticide resistance in the main vector populations, which not only threaten hope for elimination in malaria-endemic countries but also may lead to reversal where notable reductions in malaria have been documented. This communication illustrates the current status of insecticide resistance with a focus on the countries where activities are ongoing for 9 out of the 10 ICEMRs. Most of the primary malaria vectors in the ICEMR countries exhibit insecticide resistance, albeit of varying magnitude, and spanning all mechanisms of resistance. New alternatives to the insecticides currently available are still to be fully developed for deployment. Integrated vector management principles need to be better understood and encouraged, and viable insecticide resistance management strategies need to be developed and implemented.	en_US
dc.language.iso	eng
dc.publisher	American Society of Tropical Medicine and Hygiene
dc.relation.ispartofseries	American Journal of Tropical Medicine and Hygiene (ASTMH Journal)
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	Humans	en_US
dc.subject	Animals	en_US
dc.subject	Latin America/epidemiology	en_US
dc.subject	International Cooperation	en_US
dc.subject	Insecticide Resistance	en_US
dc.subject	Mosquito Control	en_US
dc.subject	Africa South of the Sahara/epidemiology	en_US
dc.subject	Anopheles/drug effects	en_US
dc.subject	Asia, Southeastern/epidemiology	en_US
dc.subject	Malaria/prevention & control	en_US
dc.title	Insecticide Resistance in Areas Under Investigation by the International Centers of Excellence for Malaria Research: A Challenge for Malaria Control and Elimination	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.4269/ajtmh.14-0844
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn	1476-1645