Outbreak of Cutaneous Leishmaniasis in Peruvian Military Personnel Undertaking Training Activities in the Amazon Basin, 2010

Fernandez, Jorge; Edgel, Kimberly A.; Ore, Marianela; Cabrera, Rufino; Saenz, Eliana; Arrasco, Juan C.; De Los Santos, Maxy B.; Sopan, Justino; Lescano Guevara, Andres Guillermo; Nunez, Jorge H.; Graf, Paul C. F.; Baldeviano, G. Christian; Carnero, Andres M.; Sanchez, Juan F.; Lucas, Carmen M.

dc.contributor.author	Ore, Marianela
dc.contributor.author	Saenz, Eliana
dc.contributor.author	Cabrera, Rufino
dc.contributor.author	Sanchez, Juan F.
dc.contributor.author	De Los Santos, Maxy B.
dc.contributor.author	Lucas, Carmen M.
dc.contributor.author	Nunez, Jorge H.
dc.contributor.author	Edgel, Kimberly A.
dc.contributor.author	Sopan, Justino
dc.contributor.author	Fernandez, Jorge
dc.contributor.author	Carnero, Andres M.
dc.contributor.author	Baldeviano, G. Christian
dc.contributor.author	Arrasco, Juan C.
dc.contributor.author	Graf, Paul C. F.
dc.contributor.author	Lescano Guevara, Andres Guillermo
dc.date.accessioned	2019-02-06T14:57:38Z
dc.date.available	2019-02-06T14:57:38Z
dc.date.issued	2015
dc.identifier.uri	https://hdl.handle.net/20.500.12866/5475
dc.description.abstract	Military personnel deployed to the Amazon Basin are at high risk for cutaneous leishmaniasis (CL). We responded to an outbreak among Peruvian Army personnel returning from short-term training in the Amazon, conducting active case detection, lesion sample collection, and risk factor assessment. The attack rate was 25% (76/303); the incubation period was 2-36 weeks (median = 8). Most cases had one lesion (66%), primarily ulcerative (49%), and in the legs (57%). Real-time polymerase chain reaction (PCR) identified Leishmania (Viannia) braziliensis (59/61 = 97%) and L. (V.) guyanensis (2/61 = 3%). Being male (risk ratio [RR] = 4.01; P = 0.034), not wearing long-sleeve clothes (RR = 1.71; P = 0.005), and sleeping in open rooms (RR = 1.80; P = 0.009) were associated with CL. Sodium stibogluconate therapy had a 41% cure rate, less than previously reported in Peru (~70%; P < 0.001). After emphasizing pre-deployment education and other basic prevention measures, trainees in the following year had lower incidence (1/278 = 0.4%; P < 0.001). Basic prevention can reduce CL risk in deployed militaries.	en_US
dc.language.iso	eng
dc.publisher	American Society of Tropical Medicine and Hygiene
dc.relation.ispartofseries	American Journal of Tropical Medicine and Hygiene (ASTMH Journal)
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	Adolescent	en_US
dc.subject	Female	en_US
dc.subject	Humans	en_US
dc.subject	Male	en_US
dc.subject	Young Adult	en_US
dc.subject	Surveys and Questionnaires	en_US
dc.subject	Peru/epidemiology	en_US
dc.subject	Disease Outbreaks	en_US
dc.subject	Real-Time Polymerase Chain Reaction	en_US
dc.subject	Military Personnel	en_US
dc.subject	Antimony Sodium Gluconate/therapeutic use	en_US
dc.subject	Leishmania braziliensis/isolation & purification	en_US
dc.subject	Leishmania guyanensis/isolation & purification	en_US
dc.subject	Leishmaniasis, Cutaneous/drug therapy/epidemiology	en_US
dc.title	Outbreak of Cutaneous Leishmaniasis in Peruvian Military Personnel Undertaking Training Activities in the Amazon Basin, 2010	en_US
dc.title.alternative	Brote de leishmaniasis cutánea en personal militar peruano que realizó actividades de entrenamiento militar en la Cuenca Amazónica, 2010	es_PE
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.4269/ajtmh.15-0107
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn	1476-1645