Universidad Peruana Cayetano Heredia

Effect of gamma irradiation on phenol content, antioxidant activity and biological activity of black maca and red maca extracts (Lepidium meyenii walp)

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dc.contributor.author Zevallos-Concha, A.
dc.contributor.author Nunez, D.
dc.contributor.author Gasco Tantachuco, Manuel Enrique
dc.contributor.author Vasquez, C.
dc.contributor.author Quispe, M.
dc.contributor.author Gonzales Rengifo, Gustavo Francisco
dc.date.accessioned 2019-02-06T14:57:42Z
dc.date.available 2019-02-06T14:57:42Z
dc.date.issued 2015
dc.identifier.uri https://hdl.handle.net/20.500.12866/5497
dc.description.abstract This study was performed to determine the effects of gamma irradiation on UV spectrum on maca, total content of polyphenols, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activities and in vivo biological activities of red and black maca extracts (Lepidium meyenii). Adult mice of the strain Swiss aged 3 months and weighing 30-35 g in average were used to determine biological activities. Daily sperm production, effect on testosterone-induced prostate hyperplasia and forced swimming test were used to determine the effect of irradiation on biological activities of maca extracts. Irradiation did not show differences in UV spectrum but improves the amount of total polyphenols in red maca as well as in black maca extracts. In both cases, black maca extract has more content of polyphenols than red maca extract (p < 0.01). Gamma irradiation significantly increased the antioxidant capacity (p < 0.05). No difference was observed in daily sperm production when irradiated and nonirradiated maca extract were administered to mice (p > 0.05). Black maca extract but not red maca extract has more swimming endurance capacity in the forced swimming test. Irradiation of black maca extract increased the swimming time to exhaustion (p < 0.05). This is not observed with red maca extract (p > 0.05). Testosterone enanthate (TE) increased significantly the ventral prostate weight. Administration of red maca extract in animals treated with TE prevented the increase in prostate weight. Irradiation did not modify effect of red maca extract on prostate weight (p > 0.05). In conclusion, irradiation does not alter the biological activities of both black maca and red maca extracts. It prevents the presence of microorganisms in the extracts of black or red maca, but the biological activities were maintained. en_US
dc.language.iso eng
dc.publisher Taylor and Francis
dc.relation.ispartofseries Toxicology Mechanisms and Methods
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Female en_US
dc.subject Male en_US
dc.subject Animals en_US
dc.subject Lepidium meyenii en_US
dc.subject red maca en_US
dc.subject Mice en_US
dc.subject black maca en_US
dc.subject Antioxidants/chemistry/pharmacology en_US
dc.subject Biological activities en_US
dc.subject gamma irradiation en_US
dc.subject Gamma Rays en_US
dc.subject Lepidium/chemistry en_US
dc.subject Phenols/chemistry en_US
dc.subject Plant Extracts/chemistry/pharmacology en_US
dc.subject polyphenols en_US
dc.subject radical-scavenging activities en_US
dc.subject Spectrophotometry, Atomic en_US
dc.subject Ultraviolet Rays en_US
dc.title Effect of gamma irradiation on phenol content, antioxidant activity and biological activity of black maca and red maca extracts (Lepidium meyenii walp) en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.3109/15376516.2015.1090512
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.01.07
dc.relation.issn 1537-6524


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