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Vaccine schedule compliance among very low birth weight infants in Lima, Peru

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dc.contributor.author Ochoa Woodell, Theresa Jean
dc.contributor.author Zea-Vera, Alonso
dc.contributor.author Bautista, Rossana
dc.contributor.author Davila, Carmen
dc.contributor.author Salazar, José Antonio
dc.contributor.author Bazán, Carlos
dc.contributor.author López, Luis
dc.contributor.author Ecker, Lucie
dc.date.accessioned 2019-02-06T14:57:43Z
dc.date.available 2019-02-06T14:57:43Z
dc.date.issued 2015
dc.identifier.uri https://hdl.handle.net/20.500.12866/5502
dc.description.abstract OBJECTIVE: There is little information about vaccine schedule compliance in very-low-birth-weight infants in developing countries. The aim of the study was to describe the compliance with the vaccine schedule among this population in Lima, Peru. PATIENTS AND METHODS: We conducted a prospective cohort study in four hospitals in Lima in infants with a birth-weight of less than 1500 g, followed from birth up to 12 months of age every 2 weeks. The date and age at administration of each vaccine was recorded RESULTS: 222 infants were enrolled. The median birth-weight was 1250 g (range 550-1499 g) and the median gestational age was 30.0 weeks (range 23-37 weeks). The mean age for the first pentavalent (DPT, Hib, HepB) and oral polio vaccine administration was 4.3 +/- 1.4 months in infants with a birth-weight of < 1000 g vs. 3.1 +/- 1.0 in infants with a birth-weight 1000-1500 g (p < 0.001); 4.1 +/- 0.9 vs. 3.3 +/- 1.1 for rotavirus (p < 0.05); and 5.1 +/- 2.1 vs. 4.3 +/- 1.8 for the 7-valent pneumococcal conjugated vaccine. Only 35% had received the three doses of oral polio and pentavalent vaccine by seven months, although by nine months 81% had received these vaccines. CONCLUSIONS: Vaccination of very-low-birth-weight infants in Peru is significantly delayed, especially in infants with a birth-weight of < 1000 g and lower gestational age. Urgent educational interventions targeting physicians and nurses should be implemented in order to improve vaccination rates and timing in these high risk populations. en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries Vaccine
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Female en_US
dc.subject Humans en_US
dc.subject Male en_US
dc.subject Infant en_US
dc.subject Time Factors en_US
dc.subject Cohort Studies en_US
dc.subject Peru/epidemiology en_US
dc.subject Prospective Studies en_US
dc.subject Developing countries en_US
dc.subject Gestational Age en_US
dc.subject Infant, Newborn en_US
dc.subject Infant, Premature en_US
dc.subject Vaccines en_US
dc.subject Guideline Adherence en_US
dc.subject Immunization Schedule en_US
dc.subject Infant, Very Low Birth Weight en_US
dc.subject Diphtheria-Tetanus-Pertussis Vaccine/administration & dosage en_US
dc.subject Haemophilus Vaccines/administration & dosage en_US
dc.subject Infant, Premature, Diseases/prevention & control en_US
dc.subject Pneumococcal Vaccines/immunology en_US
dc.subject Poliovirus Vaccine, Oral/administration & dosage/immunology en_US
dc.subject Vaccination/statistics & numerical data en_US
dc.subject Vaccines, Combined/administration & dosage en_US
dc.subject Vaccines, Conjugate/administration & dosage/immunology en_US
dc.subject Vaccines/administration & dosage en_US
dc.subject Very low birth weight infant en_US
dc.title Vaccine schedule compliance among very low birth weight infants in Lima, Peru en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1016/j.vaccine.2014.11.014
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#1.06.03
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.08
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.05
dc.relation.issn 1873-2518


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