Bed bugs (Cimex lectularius) as vectors of Trypanosoma cruzi

Castillo Neyra, Ricardo; Levy, Michael Z.; Salazar Sánchez, Renzo Sadath; Borrini-Mayori, Katty; Naquira Velarde, Cesar Gabriel; Tustin, Aaron W.

dc.contributor.author	Salazar Sánchez, Renzo Sadath
dc.contributor.author	Castillo Neyra, Ricardo
dc.contributor.author	Tustin, Aaron W.
dc.contributor.author	Borrini-Mayori, Katty
dc.contributor.author	Naquira Velarde, Cesar Gabriel
dc.contributor.author	Levy, Michael Z.
dc.date.accessioned	2019-02-06T14:57:43Z
dc.date.available	2019-02-06T14:57:43Z
dc.date.issued	2015
dc.identifier.uri	https://hdl.handle.net/20.500.12866/5505
dc.description.abstract	Populations of the common bed bug, Cimex lectularius, have recently undergone explosive growth. Bed bugs share many important traits with triatomine insects, but it remains unclear whether these similarities include the ability to transmit Trypanosoma cruzi, the etiologic agent of Chagas disease. Here, we show efficient and bidirectional transmission of T. cruzi between hosts and bed bugs in a laboratory environment. Most bed bugs that fed on experimentally infected mice acquired the parasite. A majority of previously uninfected mice became infected after a period of cohabitation with exposed bed bugs. T. cruzi was also transmitted to mice after the feces of infected bed bugs were applied directly to broken host skin. Quantitative bed bug defecation measures were similar to those of important triatomine vectors. Our findings suggest that the common bed bug may be a competent vector of T. cruzi and could pose a risk for vector-borne transmission of Chagas disease.	en_US
dc.language.iso	eng
dc.publisher	American Society of Tropical Medicine and Hygiene
dc.relation.ispartofseries	American Journal of Tropical Medicine and Hygiene (ASTMH Journal)
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.subject	Female	en_US
dc.subject	Male	en_US
dc.subject	Animals	en_US
dc.subject	Feces/parasitology	en_US
dc.subject	Trypanosoma cruzi/physiology	en_US
dc.subject	Insect Vectors/parasitology	en_US
dc.subject	Bedbugs/parasitology	en_US
dc.subject	Chagas Disease/transmission	en_US
dc.subject	Mice, Inbred BALB C/parasitology	en_US
dc.title	Bed bugs (Cimex lectularius) as vectors of Trypanosoma cruzi	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.4269/ajtmh.14-0483
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn	1476-1645