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Similarities in the Markers of Inflammation Between Men With Syphilis and Women With Increased Risk of HIV Acquisition

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dc.contributor.author Kojima, Noah
dc.contributor.author Bristow, Claire C.
dc.contributor.author Maecker, Holden
dc.contributor.author Rosenberg-Hasson, Yael
dc.contributor.author León Sandoval, Segundo Ramos
dc.contributor.author Vargas Rivera, Silver Keith
dc.contributor.author Konda, Kelika A.
dc.contributor.author Caceres Palacios, Carlos Fernando
dc.contributor.author Klausner, Jeffrey D.
dc.date.accessioned 2019-02-06T14:59:05Z
dc.date.available 2019-02-06T14:59:05Z
dc.date.issued 2015
dc.identifier.uri https://hdl.handle.net/20.500.12866/5522
dc.description.abstract We appreciated the recent study by Masson et al that utilized multiplex bead-based enzyme-linked immunosorbent assays (MBB-ELISAs) to associate human immunodeficiency virus (HIV) seroconversion with raised genital inflammatory cytokines from samples from cervicovaginal lavages from KwaZulu-Natal, South Africa. The authors found that several cytokines, including macrophage inflammatory protein 1B, macrophage inflammatory protein 1A, interferon gamma-induced protein 10, and interleukin 8 levels, were elevated in HIV seroconverters compared with nonconverters. We conducted a pilot study using MBB-ELISAs to simultaneously screen for 63 cytokines in sera samples collected from patients with and without syphilis in Lima, Peru. Interestingly our study found elevated levels of similar chemotactic, inflammatory, and hematopoietic cytokines to the ones seen in the study by Masson et al. en_US
dc.language.iso eng
dc.publisher Oxford University Press
dc.relation.ispartofseries Clinical Infectious Diseases
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Female en_US
dc.subject Humans en_US
dc.subject Chemokines/analysis en_US
dc.subject Cytokines/analysis en_US
dc.subject Genital Diseases, Female/diagnosis en_US
dc.subject Genitalia, Female/immunology/virology en_US
dc.subject HIV Infections/immunology/transmission en_US
dc.title Similarities in the Markers of Inflammation Between Men With Syphilis and Women With Increased Risk of HIV Acquisition en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1093/cid/civ842
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.08
dc.relation.issn 1537-6591


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