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Proteins of Bartonella bacilliformis: Candidates for Vaccine Development

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dc.contributor.author Henriquez-Camacho, Cesar
dc.contributor.author Ventosilla, Palmira
dc.contributor.author Minnick, Michael F.
dc.contributor.author Ruiz, Joaquim
dc.contributor.author Maguiña Vargas, Ciro
dc.date.accessioned 2019-02-06T14:59:06Z
dc.date.available 2019-02-06T14:59:06Z
dc.date.issued 2015
dc.identifier.uri https://hdl.handle.net/20.500.12866/5527
dc.description.abstract Bartonella bacilliformis is the etiologic agent of Carrion's disease or Oroya fever. B. bacilliformis infection represents an interesting model of human host specificity. The notable differences in clinical presentations of Carrion's disease suggest complex adaptations by the bacterium to the human host, with the overall objectives of persistence, maintenance of a reservoir state for vectorial transmission, and immune evasion. These events include a multitude of biochemical and genetic mechanisms involving both bacterial and host proteins. This review focuses on proteins involved in interactions between B. bacilliformis and the human host. Some of them (e.g., flagellin, Brps, IalB, FtsZ, Hbp/Pap31, and other outer membrane proteins) are potential protein antigen candidates for a synthetic vaccine. en_US
dc.language.iso eng
dc.publisher Hindawi
dc.relation.ispartofseries International Journal of Peptides
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Proteins en_US
dc.subject Bartonella bacilliformis en_US
dc.subject Vaccine Development en_US
dc.title Proteins of Bartonella bacilliformis: Candidates for Vaccine Development en_US
dc.type info:eu-repo/semantics/review
dc.identifier.doi https://doi.org/10.1155/2015/702784
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#1.06.03
dc.relation.issn 1687-9775


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