Proteins of Bartonella bacilliformis: Candidates for Vaccine Development

Ventosilla, Palmira; Minnick, Michael F.; Ruiz, Joaquim; Henriquez-Camacho, Cesar; Maguiña Vargas, Ciro

dc.contributor.author	Henriquez-Camacho, Cesar
dc.contributor.author	Ventosilla, Palmira
dc.contributor.author	Minnick, Michael F.
dc.contributor.author	Ruiz, Joaquim
dc.contributor.author	Maguiña Vargas, Ciro
dc.date.accessioned	2019-02-06T14:59:06Z
dc.date.available	2019-02-06T14:59:06Z
dc.date.issued	2015
dc.identifier.uri	https://hdl.handle.net/20.500.12866/5527
dc.description.abstract	Bartonella bacilliformis is the etiologic agent of Carrion's disease or Oroya fever. B. bacilliformis infection represents an interesting model of human host specificity. The notable differences in clinical presentations of Carrion's disease suggest complex adaptations by the bacterium to the human host, with the overall objectives of persistence, maintenance of a reservoir state for vectorial transmission, and immune evasion. These events include a multitude of biochemical and genetic mechanisms involving both bacterial and host proteins. This review focuses on proteins involved in interactions between B. bacilliformis and the human host. Some of them (e.g., flagellin, Brps, IalB, FtsZ, Hbp/Pap31, and other outer membrane proteins) are potential protein antigen candidates for a synthetic vaccine.	en_US
dc.language.iso	eng
dc.publisher	Hindawi
dc.relation.ispartofseries	International Journal of Peptides
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject	Proteins	en_US
dc.subject	Bartonella bacilliformis	en_US
dc.subject	Vaccine Development	en_US
dc.title	Proteins of Bartonella bacilliformis: Candidates for Vaccine Development	en_US
dc.type	info:eu-repo/semantics/review
dc.identifier.doi	https://doi.org/10.1155/2015/702784
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#1.06.03
dc.relation.issn	1687-9775