The molecular epidemiology of Treponema pallidum subspecies pallidum

Giacani, Lorenzo; Centurion-Lara, Arturo; Ma, Daphne Y.

dc.contributor.author	Ma, Daphne Y.
dc.contributor.author	Giacani, Lorenzo
dc.contributor.author	Centurion-Lara, Arturo
dc.date.accessioned	2019-02-06T14:59:07Z
dc.date.available	2019-02-06T14:59:07Z
dc.date.issued	2015
dc.identifier.uri	https://hdl.handle.net/20.500.12866/5552
dc.description.abstract	Pathogens adapt and evolve in response to pressures exerted by host environments, leading to generation of genetically diverse variants. Treponema pallidum subspecies pallidum displays a substantial amount of interstrain diversity. These variants have been identified in various parts of the world, indicating transmission linkage between geographical regions. Genotyping is based on molecular characterisation of various loci in the syphilis treponeme genome, but still require further development and continued research, as new bacterial types are continually being detected. The goal for studying the molecular epidemiology of Treponema pallidum variants is the global monitoring of the transmission of genetically distinct organisms with different drug sensitivities and, potentially, different virulence proprieties.	en_US
dc.language.iso	eng
dc.publisher	CSIRO Publishing
dc.relation.ispartofseries	Sexual Health
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject	Molecular epidemiology	en_US
dc.subject	Treponema pallidum	en_US
dc.title	The molecular epidemiology of Treponema pallidum subspecies pallidum	en_US
dc.type	info:eu-repo/semantics/review
dc.identifier.doi	https://doi.org/10.1071/SH14197
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.08
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.05
dc.relation.issn	1449-8987