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CD133 in breast cancer cells and in breast cancer stem cells as another target for immunotherapy

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dc.contributor.author Tume, Luis
dc.contributor.author Paco, Karen
dc.contributor.author Ubidia-Incio, Roberto
dc.contributor.author Moya, Jeel
dc.date.accessioned 2019-02-22T14:56:09Z
dc.date.available 2019-02-22T14:56:09Z
dc.date.issued 2016
dc.identifier.uri https://hdl.handle.net/20.500.12866/5853
dc.description.abstract Breast cancer consists of a heterogeneous group of tumors with different features, biology and treatments. Cancer stem cells (CSCs) have been associated with an aggressive cellular behavior, resistance to chemotherapy and radiotherapy in many types of neoplasms, and a strong correlation between prominin-1 (CD133) expression in cancer stem cells from different types of cancer exist. A discussion is presented on recent immunotherapeutic strategies that target CD133 in breast CSCs. Furthermore, it is suggested that immunotherapy targeting CD133 breast CSCs and/or in combination with other current treatments result in a better outcome. en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartof urn:issn:1665-9201
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject Breast cancer en_US
dc.subject CD133 en_US
dc.subject CSCs en_US
dc.subject Immunotherapy en_US
dc.title CD133 in breast cancer cells and in breast cancer stem cells as another target for immunotherapy en_US
dc.type info:eu-repo/semantics/review
dc.identifier.doi https://doi.org/10.1016/j.gamo.2016.01.003
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.00 es_PE


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