Mycobacterium abscessus Complex Cutaneous Infection

Porudominsky, R.; Gotuzzo Herencia, José Eduardo

dc.contributor.author	Porudominsky, R.
dc.contributor.author	Gotuzzo Herencia, José Eduardo
dc.date.accessioned	2019-03-05T15:23:26Z
dc.date.available	2019-03-05T15:23:26Z
dc.date.issued	2018
dc.identifier.uri	https://hdl.handle.net/20.500.12866/5873
dc.description.abstract	Purpose of Review: The worldwide increase in skin infections due to Mycobacterium abscessus, especially in Latin America, and its difficult diagnosis and treatment, makes a review of literature crucial in reminding and updating physicians about its presentation, diagnosing techniques, and management. Recent Findings: Outbreaks are associated with cosmetic surgeries and medical tourism, but any kind of skin lesion can become infected presenting as negative typical cultures and unsuccessful empirical treatments; therefore, a high clinical suspicion is required. Molecular techniques are promising new diagnosing alternatives and treatment should be guided by susceptibility tests. Summary: Mycobacterium abscessus complex skin infections are concerning due to difficult diagnosis, burdensome treatment, drug resistance, and high cost of management. Usually associated to cosmetic procedures, especially medical tourism, it can also be related to other incisions (C-section, injections, laparoscopy, etc.). Diagnosis requires clinical suspicion and consists of phenotypic and molecular methods to recognize the organisms to a subspecies level. Drug treatment frequently involves surgical debridement and antibiotics with special concern about resistance and adverse events.	en_US
dc.language.iso	eng
dc.publisher	Springer
dc.relation.ispartofseries	Current Tropical Medicine Reports
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject	Skin	en_US
dc.subject	systemic lupus erythematosus	en_US
dc.subject	human	en_US
dc.subject	gastrointestinal disease	en_US
dc.subject	priority journal	en_US
dc.subject	skin disease	en_US
dc.subject	moxifloxacin	en_US
dc.subject	azithromycin	en_US
dc.subject	Infection	en_US
dc.subject	Review	en_US
dc.subject	imipenem	en_US
dc.subject	real time polymerase chain reaction	en_US
dc.subject	prednisolone	en_US
dc.subject	antibiotic therapy	en_US
dc.subject	molecular diagnosis	en_US
dc.subject	cost benefit analysis	en_US
dc.subject	clarithromycin	en_US
dc.subject	mycobacteriosis	en_US
dc.subject	variable number of tandem repeat	en_US
dc.subject	restriction fragment length polymorphism	en_US
dc.subject	immunosuppressive treatment	en_US
dc.subject	nausea	en_US
dc.subject	vomiting	en_US
dc.subject	cellulitis	en_US
dc.subject	amikacin	en_US
dc.subject	cefoxitin	en_US
dc.subject	high performance liquid chromatography	en_US
dc.subject	debridement	en_US
dc.subject	Cutaneous	en_US
dc.subject	leukopenia	en_US
dc.subject	clofazimine	en_US
dc.subject	ototoxicity	en_US
dc.subject	azathioprine	en_US
dc.subject	tigecycline	en_US
dc.subject	skin redness	en_US
dc.subject	abscessus	en_US
dc.subject	bacterial skin disease	en_US
dc.subject	battle injury	en_US
dc.subject	bolletii	en_US
dc.subject	esthetic surgery	en_US
dc.subject	liver injury	en_US
dc.subject	massiliense	en_US
dc.subject	matrix-assisted laser desorption-ionization mass spectrometry	en_US
dc.subject	medical tourism	en_US
dc.subject	minocycline	en_US
dc.subject	multilocus enzyme electrophoresis	en_US
dc.subject	Mycobacterium abscessus	en_US
dc.subject	Nontuberculous mycobacteria	en_US
dc.subject	Rapidly growing mycobacteria	en_US
dc.subject	rifabutin	en_US
dc.subject	trigger finger	en_US
dc.title	Mycobacterium abscessus Complex Cutaneous Infection	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.1007/s40475-018-0151-9
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.06
dc.relation.issn	2196-3045