Universidad Peruana Cayetano Heredia

Latin Americans show wide-spread Converso ancestry and imprint of local Native ancestry on physical appearance

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dc.contributor.author Chacón-Duque, Juan-Camilo
dc.contributor.author Adhikari, Kaustubh
dc.contributor.author Fuentes-Guajardo, Macarena
dc.contributor.author Mendoza-Revilla, Javier
dc.contributor.author Acuña-Alonzo, Victor
dc.contributor.author Barquera, Rodrigo
dc.contributor.author Quinto-Sánchez, Mirsha
dc.contributor.author Gómez-Valdés, Jorge
dc.contributor.author Everardo Martínez, Paola
dc.contributor.author Villamil-Ramírez, Hugo
dc.contributor.author Hünemeier, Tabita
dc.contributor.author Ramallo, Virginia
dc.contributor.author Silva de Cerqueira, Caio C.
dc.contributor.author Hurtado, Malena
dc.contributor.author Villegas, Valeria
dc.contributor.author Granja, Vanessa
dc.contributor.author Villena, Mercedes
dc.contributor.author Vásquez, Rene
dc.contributor.author Llop, Elena
dc.contributor.author Sandoval, Jose R.
dc.contributor.author Salazar-Granara, Alberto A.
dc.contributor.author Parolin, Maria-Laura
dc.contributor.author Sandoval, Karla
dc.contributor.author Peñaloza-Espinosa, Rosenda I.
dc.contributor.author Rangel-Villalobos, Hector
dc.contributor.author Winkler, Cheryl A.
dc.contributor.author Klitz, William
dc.contributor.author Bravi, Claudio
dc.contributor.author Molina, Julio
dc.contributor.author Corach, Daniel
dc.contributor.author Barrantes, Ramiro
dc.contributor.author Gomes, Veronica
dc.contributor.author Resende, Carlos
dc.contributor.author Gusmão, Leonor
dc.contributor.author Amorim, Antonio
dc.contributor.author Xue, Yali
dc.contributor.author Dugoujon, Jean-Michel
dc.contributor.author Moral, Pedro
dc.contributor.author González-José, Rolando
dc.contributor.author Schuler-Faccini, Lavinia
dc.contributor.author Salzano, Francisco M.
dc.contributor.author Bortolini, Maria-Catira
dc.contributor.author Canizales-Quinteros, Samuel
dc.contributor.author Poletti, Giovanni
dc.contributor.author Gallo López-Aliaga, Carla Maria
dc.contributor.author Bedoya, Gabriel
dc.contributor.author Rothhammer, Francisco
dc.contributor.author Balding, David
dc.contributor.author Hellenthal, Garrett
dc.contributor.author Ruiz-Linares, Andres
dc.date.accessioned 2019-03-05T15:23:28Z
dc.date.available 2019-03-05T15:23:28Z
dc.date.issued 2018
dc.identifier.uri https://hdl.handle.net/20.500.12866/5891
dc.description.abstract Historical records and genetic analyses indicate that Latin Americans trace their ancestry mainly to the intermixing (admixture) of Native Americans, Europeans and Sub-Saharan Africans. Using novel haplotype-based methods, here we infer sub-continental ancestry in over 6,500 Latin Americans and evaluate the impact of regional ancestry variation on physical appearance. We find that Native American ancestry components in Latin Americans correspond geographically to the present-day genetic structure of Native groups, and that sources of non-Native ancestry, and admixture timings, match documented migratory flows. We also detect South/East Mediterranean ancestry across Latin America, probably stemming mostly from the clandestine colonial migration of Christian converts of non-European origin (Conversos). Furthermore, we find that ancestry related to highland (Central Andean) versus lowland (Mapuche) Natives is associated with variation in facial features, particularly nose morphology, and detect significant differences in allele frequencies between these groups at loci previously associated with nose morphology in this sample. en_US
dc.language.iso eng
dc.publisher Springer Nature
dc.relation.ispartofseries Nature Communications
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject American Indian en_US
dc.subject anatomy and histology en_US
dc.subject genetics en_US
dc.subject haplotype en_US
dc.subject Haplotypes en_US
dc.subject human en_US
dc.subject Human Migration en_US
dc.subject Humans en_US
dc.subject Indians, North American en_US
dc.subject Indians, South American en_US
dc.subject Mexico en_US
dc.subject migration en_US
dc.subject nose en_US
dc.subject Nose en_US
dc.subject South America en_US
dc.title Latin Americans show wide-spread Converso ancestry and imprint of local Native ancestry on physical appearance en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1038/s41467-018-07748-z
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#1.06.03
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#1.04.00
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#1.03.00
dc.relation.issn 2041-1723


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