Universidad Peruana Cayetano Heredia

Exercise heart rates in patients with hypertrophic cardiomyopathy

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dc.contributor.author Luo, H.C.
dc.contributor.author Dimaano, V.L.
dc.contributor.author Kembro, J.M.
dc.contributor.author Hilser, A.
dc.contributor.author Hurtado-De-Mendoza, D.
dc.contributor.author Pozios, I.
dc.contributor.author Tomas, M.S.
dc.contributor.author Yalcin, H.
dc.contributor.author Dolores-Cerna, K.
dc.contributor.author Mormontoy, W.
dc.contributor.author Aon, M.A.
dc.contributor.author Cameron, D.
dc.contributor.author Bluemke, D.A.
dc.contributor.author Stewart, K.J.
dc.contributor.author Russell, S.D.
dc.contributor.author Cordova, J.G.
dc.contributor.author Abraham, T.P.
dc.contributor.author Abraham, M.R.
dc.date.accessioned 2019-04-24T18:23:49Z
dc.date.available 2019-04-24T18:23:49Z
dc.date.issued 2015
dc.identifier.uri https://hdl.handle.net/20.500.12866/6457
dc.description.abstract The exercise heart rate (HR) profile and its relation to cardiac function and arrhythmias were investigated in patients with hypertrophic cardiomyopathy (HC). Chronotropic response (CR) and heart rate recovery (HRR) were computed during and after treadmill exercise testing in 273 patients with HC and 95 age-matched healthy controls. Patients with HC had higher prevalence of chronotropic incompetence and lower HRR1-5min compared with controls. Exercise capacity, diastolic function (assessed by E/e') and left atrial volume index were associated with HRR1min and CR in HC. Septal myectomy was associated with reduction in chronotropic incompetence but did not affect HRR1min. In conclusion, impaired CR and HRR1min are associated with advanced disease and do not appear to be independent clinical markers indicating high-risk status in HC. Improving CR by titrating doses of negative chronotropic agents, myectomy, and atrial pacing may be useful to increase exercise capacity in patients with HC. en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries American Journal of Cardiology
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject adult en_US
dc.subject Article en_US
dc.subject chronotropism en_US
dc.subject controlled study en_US
dc.subject diastole en_US
dc.subject exercise en_US
dc.subject female en_US
dc.subject heart function en_US
dc.subject heart left atrium en_US
dc.subject heart rate en_US
dc.subject heart rate recovery en_US
dc.subject heart volume en_US
dc.subject human en_US
dc.subject hypertrophic cardiomyopathy en_US
dc.subject major clinical study en_US
dc.subject male en_US
dc.subject muscle resection en_US
dc.subject priority journal en_US
dc.subject treadmill exercise en_US
dc.subject Cardiomyopathy, Hypertrophic en_US
dc.subject computer assisted tomography en_US
dc.subject convalescence en_US
dc.subject Doppler echocardiography en_US
dc.subject electrocardiography en_US
dc.subject exercise en_US
dc.subject exercise test en_US
dc.subject follow up en_US
dc.subject heart left ventricle function en_US
dc.subject heart rate en_US
dc.subject heart ventricle en_US
dc.subject middle aged en_US
dc.subject pathophysiology en_US
dc.subject physiology en_US
dc.subject positron emission tomography en_US
dc.subject procedures en_US
dc.subject prognosis en_US
dc.subject retrospective study en_US
dc.subject severity of illness index en_US
dc.subject Cardiomyopathy, Hypertrophic en_US
dc.subject Echocardiography, Doppler, Color en_US
dc.subject Electrocardiography en_US
dc.subject Exercise en_US
dc.subject Exercise Test en_US
dc.subject Female en_US
dc.subject Follow-Up Studies en_US
dc.subject Heart Rate en_US
dc.subject Heart Ventricles en_US
dc.subject Humans en_US
dc.subject Male en_US
dc.subject Middle Aged en_US
dc.subject Positron-Emission Tomography en_US
dc.subject Prognosis en_US
dc.subject Recovery of Function en_US
dc.subject Retrospective Studies en_US
dc.subject Severity of Illness Index en_US
dc.subject Tomography, X-Ray Computed en_US
dc.subject Ventricular Function, Left en_US
dc.title Exercise heart rates in patients with hypertrophic cardiomyopathy en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1016/j.amjcard.2015.01.548
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.04
dc.relation.issn 1879-1913


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