Universidad Peruana Cayetano Heredia

Myocardial Injury After Noncardiac Surgery (MINS) in Vascular Surgical Patients: A Prospective Observational Cohort Study

Mostrar el registro sencillo del ítem

dc.contributor.author Biccard, B.M.
dc.contributor.author Scott, D.J.A.
dc.contributor.author Chan, M.T.V.
dc.contributor.author Archbold, A.
dc.contributor.author Wang, C.-Y.
dc.contributor.author Sigamani, A.
dc.contributor.author Urrútia, G.
dc.contributor.author Cruz, P.
dc.contributor.author Srinathan, S.K.
dc.contributor.author Szalay, D.
dc.contributor.author Harlock, J.
dc.contributor.author Tittley, J.G.
dc.contributor.author Rapanos, T.
dc.contributor.author Elias, F.
dc.contributor.author Jacka, M.J.
dc.contributor.author Málaga Rodríguez, Germán Javier
dc.contributor.author Abraham, V.
dc.contributor.author Berwanger, O.
dc.contributor.author Montes, F.R.
dc.contributor.author Heels-Ansdell, D.M.
dc.contributor.author Hutcherson, M.T.
dc.contributor.author Chow, C.K.
dc.contributor.author Polanczyk, C.A.
dc.contributor.author Szczeklik, W.
dc.contributor.author Ackland, G.L.
dc.contributor.author Dubois, L.
dc.contributor.author Sapsford, R.J.
dc.contributor.author Williams, C.
dc.contributor.author Cortés, O.L.
dc.contributor.author Le Mananch, Y.
dc.contributor.author Devereaux, P.J.
dc.date.accessioned 2019-04-24T18:23:51Z
dc.date.available 2019-04-24T18:23:51Z
dc.date.issued 2018
dc.identifier.uri https://hdl.handle.net/20.500.12866/6459
dc.description.abstract Objective: To determine the prognostic relevance, clinical characteristics, and 30-day outcomes associated with myocardial injury after noncardiac surgery (MINS) in vascular surgical patients. Background: MINS has been independently associated with 30-day mortality after noncardiac surgery. The characteristics and prognostic importance of MINS in vascular surgery patients are poorly described. Methods: This was an international prospective cohort study of 15,102 noncardiac surgery patients 45 years or older, of whom 502 patients underwent vascular surgery. All patients had fourth-generation plasma troponin T (TnT) concentrations measured during the first 3 postoperative days. MINS was defined as a TnT of 0.03 ng/mL of higher secondary to ischemia. The objectives of the present study were to determine (i) if MINS is prognostically important in vascular surgical patients, (ii) the clinical characteristics of vascular surgery patients with and without MINS, (iii) the 30-day outcomes for vascular surgery patients with and without MINS, and (iv) the proportion of MINS that probably would have gone undetected without routine troponin monitoring. Results: The incidence of MINS in the vascular surgery patients was 19.1% (95% confidence interval (CI), 15.7%-22.6%). 30-day all-cause mortality in the vascular cohort was 12.5% (95% CI 7.3%-20.6%) in patients with MINS compared with 1.5% (95% CI 0.7%-3.2%) in patients without MINS (P < 0.001). MINS was independently associated with 30-day mortality in vascular patients (odds ratio, 9.48; 95% CI, 3.46-25.96). The 30-day mortality was similar in MINS patients with (15.0%; 95% CI, 7.1-29.1) and without an ischemic feature (12.2%; 95% CI, 5.3-25.5, P = 0.76). The proportion of vascular surgery patients who suffered MINS without overt evidence of myocardial ischemia was 74.1% (95% CI, 63.6-82.4). Conclusions: Approximately 1 in 5 patients experienced MINS after vascular surgery. MINS was independently associated with 30-day mortality. The majority of patients with MINS were asymptomatic and would have gone undetected without routine postoperative troponin measurement. en_US
dc.language.iso eng
dc.publisher Wolters Kluwer Health
dc.relation.ispartofseries Annals of Surgery
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject troponin T en_US
dc.subject adult en_US
dc.subject aged en_US
dc.subject all cause mortality en_US
dc.subject artery reconstruction en_US
dc.subject Article en_US
dc.subject atrial fibrillation en_US
dc.subject cardiac imaging en_US
dc.subject cerebrovascular surgery en_US
dc.subject clinical outcome en_US
dc.subject cohort analysis en_US
dc.subject congestive heart failure en_US
dc.subject coronary artery bypass graft en_US
dc.subject coronary artery disease en_US
dc.subject electrocardiogram en_US
dc.subject endovascular aneurysm repair en_US
dc.subject female en_US
dc.subject health care personnel en_US
dc.subject heart arrest en_US
dc.subject heart muscle injury en_US
dc.subject heart muscle revascularization en_US
dc.subject human en_US
dc.subject kidney dysfunction en_US
dc.subject length of stay en_US
dc.subject major clinical study en_US
dc.subject male en_US
dc.subject middle aged en_US
dc.subject observational study en_US
dc.subject percutaneous coronary intervention en_US
dc.subject postoperative complication en_US
dc.subject postoperative period en_US
dc.subject priority journal en_US
dc.subject prognosis en_US
dc.subject prospective study en_US
dc.subject Q wave en_US
dc.subject scintiscanning en_US
dc.subject ST segment depression en_US
dc.subject ST segment elevation en_US
dc.subject surgical mortality en_US
dc.subject surgical patient en_US
dc.subject T wave inversion en_US
dc.subject vascular surgery en_US
dc.title Myocardial Injury After Noncardiac Surgery (MINS) in Vascular Surgical Patients: A Prospective Observational Cohort Study en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1097/SLA.0000000000002290
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.11
dc.relation.issn 1528-1140


Ficheros en el ítem

Ficheros Tamaño Formato Ver

No hay ficheros asociados a este ítem.

Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem

info:eu-repo/semantics/restrictedAccess Excepto si se señala otra cosa, la licencia del ítem se describe como info:eu-repo/semantics/restrictedAccess

Buscar en el Repositorio


Listar

Panel de Control

Estadísticas