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Opt-out screening strategy for HIV infection among patients attending emergency departments: systematic review and meta-analysis

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dc.contributor.author Henriquez-Camacho, C.
dc.contributor.author Villafuerte-Gutierrez, P.
dc.contributor.author Pérez-Molina, J.A.
dc.contributor.author Losa, J.
dc.contributor.author Gotuzzo Herencia, José Eduardo
dc.contributor.author Cheyne, N.
dc.date.accessioned 2019-04-24T18:23:52Z
dc.date.available 2019-04-24T18:23:52Z
dc.date.issued 2016
dc.identifier.uri https://hdl.handle.net/20.500.12866/6468
dc.description.abstract Objectives: International health agencies have promoted nontargeted universal (opt-out) HIV screening tests in different settings, including emergency departments (EDs). We performed a systematic review and meta-analysis to assess the testing uptake of strategies (opt-in targeted, opt-in nontargeted and opt-out) to detect new cases of HIV infection in EDs. Methods: We searched the Pubmed and Embase databases, from 1984 to April 2015, for opt-in and opt-out HIV diagnostic strategies used in EDs. Randomized controlled or quasi experimental studies were included. We assessed the percentage of positive individuals tested for HIV infection in each programme (opt-in and opt-out strategies). The mean percentage was estimated by combining studies in a random-effect meta-analysis. The percentages of individuals tested in the programmes were compared in a random-effect meta-regression model. Data were analysed using stata version 12. Quality assessments were performed using the Newcastle−Ottawa Scale. Results: Of the 90 papers identified, 28 were eligible for inclusion. Eight trials used opt-out, 18 trials used opt-in, and two trials used both to detect new cases of HIV infection. The test was accepted and taken by 75 155 of 172 237 patients (44%) in the opt-out strategy, and 73 581 of 382 992 patients (19%) in the opt-in strategy. The prevalence of HIV infection detected by the opt-out strategy was 0.40% (373 cases), that detected by the opt-in nontargeted strategy was 0.52% (419 cases), and that detected by the opt-in targeted strategy was 1.06% (52 cases). Conclusions: In this meta-analysis, the testing uptake of the opt-out strategy was not different from that of the opt-in strategy to detect new cases of HIV infection in EDs. en_US
dc.language.iso eng
dc.publisher Wiley
dc.relation.ispartofseries HIV Medicine
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject emergency ward en_US
dc.subject health care utilization en_US
dc.subject HIV test en_US
dc.subject human en_US
dc.subject Human immunodeficiency virus infection en_US
dc.subject Human immunodeficiency virus prevalence en_US
dc.subject meta analysis en_US
dc.subject priority journal en_US
dc.subject randomized controlled trial (topic) en_US
dc.subject systematic review en_US
dc.subject female en_US
dc.subject hospital emergency service en_US
dc.subject Human immunodeficiency virus infection en_US
dc.subject male en_US
dc.subject mass screening en_US
dc.subject patient attitude en_US
dc.subject procedures en_US
dc.subject Emergency Service, Hospital en_US
dc.subject Female en_US
dc.subject HIV Infections en_US
dc.subject Humans en_US
dc.subject Male en_US
dc.subject Mass Screening en_US
dc.subject Patient Acceptance of Health Care en_US
dc.subject Randomized Controlled Trials as Topic en_US
dc.title Opt-out screening strategy for HIV infection among patients attending emergency departments: systematic review and meta-analysis en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1111/hiv.12474
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.02
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.03.08|https://purl.org/pe-repo/ocde/ford#3.01.055
dc.relation.issn 1468-1293

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