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dc.contributor.author | Cornejo-Olivas, M. | |
dc.contributor.author | Espinoza Huertas, Keren Antonieta | |
dc.contributor.author | Velit-Salazar, M.R. | |
dc.contributor.author | Veliz-Otani, D. | |
dc.contributor.author | Tirado-Hurtado, I. | |
dc.contributor.author | Inca-Martinez, M. | |
dc.contributor.author | Silva-Paredes, G. | |
dc.contributor.author | Milla-Neyra, K. | |
dc.contributor.author | Marca, V. | |
dc.contributor.author | Ortega, O. | |
dc.contributor.author | Mazzetti, P. | |
dc.date.accessioned | 2019-04-24T18:23:53Z | |
dc.date.available | 2019-04-24T18:23:53Z | |
dc.date.issued | 2015 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12866/6472 | |
dc.description.abstract | Neurogenetics, the science that studies the genetic basis of the development and function of the nervous system, is a discipline of recent development in Peru, an emerging Latin American country. Herein, we review the clinical, scientific and ethical aspects regarding the development of this discipline, starting with the first molecular diagnosis of neurogenetic diseases, to family and population-based genetic association studies. Neurogenetics in Peru aims to better explain the epidemiology of monogenic and complex neurodegenerative disorders that will help in implementing public health policies for these disorders. The characterization of Peru and its health system, legal issues regarding rare diseases and the historical milestones in neurogenetics are also discussed. | en_US |
dc.language.iso | eng | |
dc.publisher | Springer | |
dc.relation.ispartofseries | Journal of Community Genetics | |
dc.rights | info:eu-repo/semantics/restrictedAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es | |
dc.subject | Alzheimer disease | en_US |
dc.subject | Article | en_US |
dc.subject | degenerative disease | en_US |
dc.subject | developmental genetics | en_US |
dc.subject | gene | en_US |
dc.subject | gene expression | en_US |
dc.subject | gene mutation | en_US |
dc.subject | genetic association | en_US |
dc.subject | genetic counseling | en_US |
dc.subject | genetic polymorphism | en_US |
dc.subject | genetic risk | en_US |
dc.subject | genetic screening | en_US |
dc.subject | genetics | en_US |
dc.subject | genotype | en_US |
dc.subject | geographic distribution | en_US |
dc.subject | health care cost | en_US |
dc.subject | HTT gene | en_US |
dc.subject | human | en_US |
dc.subject | Huntington chorea | en_US |
dc.subject | incidence | en_US |
dc.subject | life expectancy | en_US |
dc.subject | molecular diagnosis | en_US |
dc.subject | molecular pathology | en_US |
dc.subject | neurogenetics | en_US |
dc.subject | neurologic disease | en_US |
dc.subject | neuropathology | en_US |
dc.subject | Peru | en_US |
dc.subject | population genetics | en_US |
dc.subject | priority journal | en_US |
dc.subject | PSEN1 gene | en_US |
dc.subject | quality of life | en_US |
dc.subject | risk assessment | en_US |
dc.subject | South and Central America | en_US |
dc.title | Neurogenetics in Peru: clinical, scientific and ethical perspectives | en_US |
dc.type | info:eu-repo/semantics/article | |
dc.identifier.doi | https://doi.org/10.1007/s12687-015-0239-z | |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#1.06.07 | |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.03.09 | |
dc.subject.ocde | https://purl.org/pe-repo/ocde/ford#3.03.05 | |
dc.relation.issn | 1868-6001 |
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