PrEP implementation: Moving from trials to policy and practice

O'Reilly, K.R.; Baggaley, R.; Caceres Palacios, Carlos Fernando; Mayer, K.H.

dc.contributor.author	Caceres Palacios, Carlos Fernando
dc.contributor.author	O'Reilly, K.R.
dc.contributor.author	Mayer, K.H.
dc.contributor.author	Baggaley, R.
dc.date.accessioned	2019-04-24T18:23:54Z
dc.date.available	2019-04-24T18:23:54Z
dc.date.issued	2015
dc.identifier.uri	https://hdl.handle.net/20.500.12866/6479
dc.description.abstract	Introduction: It is increasingly clear that the HIV response will not be sustainable if the number of infections is not significantly reduced. Discussion: For two decades, research has been ongoing to identify new behavioural and biomedical strategies to prevent HIV infection. In the past few years, the efficacy of several new strategies has been demonstrated, including oral pre-exposure prophylaxis (PrEP; i.e. daily use of tenofovir/emtricitabine). Because several social, political and logistic barriers remain, however, optimal PrEP implementation will require a better dissemination of new evidence in a number of areas and additional implementation research from various disciplinary perspectives (i.e. social science, policy and ethics; health systems; and economics, including costeffectiveness studies). Discussion of new evidence on those topics, as well as case studies of potential PrEP implementation in diverse environments, can improve the understanding of the role that PrEP may play in addressing the global HIV/AIDS epidemic. In light of these needs, the Network for Multidisciplinary Studies in ARV-based HIV Prevention (NEMUS) and the World Health Organization (WHO) were honoured to co-organize a special issue of JIAS aimed at contributing to a scholarly discussion of current conditions surrounding PrEP implementation, potential impact and efficiency, social science concerns and the study of PrEP implementation in specific country cases. The papers included in this monograph identify and cover many of the main aspects of the complex yet promising discussions around PrEP implementation today. Conclusions: This is a collection of timely contributions from global leaders in HIV research and policy that addresses geographic diversity, uses a trans-disciplinary approach and covers a variety of the complex issues raised by PrEP. As this publication will become accessible to all, we hope that it will remain a valuable resource for policy makers, programme managers, researchers and activists around the world at a moment of a paradigm shift of the global response to HIV.	en_US
dc.language.iso	eng
dc.publisher	Wiley
dc.relation.ispartofseries	Journal of the International AIDS Society
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject	emtricitabine plus tenofovir disoproxil	en_US
dc.subject	anti human immunodeficiency virus agent	en_US
dc.subject	Article	en_US
dc.subject	clinical trial (topic)	en_US
dc.subject	cost effectiveness analysis	en_US
dc.subject	health care planning	en_US
dc.subject	health care policy	en_US
dc.subject	human	en_US
dc.subject	Human immunodeficiency virus infection	en_US
dc.subject	infection prevention	en_US
dc.subject	information dissemination	en_US
dc.subject	motivation	en_US
dc.subject	practice guideline	en_US
dc.subject	pre-exposure prophylaxis	en_US
dc.subject	priority journal	en_US
dc.subject	world health organization	en_US
dc.subject	HIV Infections	en_US
dc.subject	Anti-HIV Agents	en_US
dc.subject	Clinical Trials as Topic	en_US
dc.subject	HIV Infections	en_US
dc.subject	Humans	en_US
dc.subject	Pre-Exposure Prophylaxis	en_US
dc.title	PrEP implementation: Moving from trials to policy and practice	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.7448/IAS.18.4.20222
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#3.03.08
dc.relation.issn	1758-2652