Universidad Peruana Cayetano Heredia

Diagnostic validity of the generalized anxiety disorder - 7 (GAD-7) among pregnant women

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dc.contributor.author Zhong, Q.Y.
dc.contributor.author Gelaye, B.
dc.contributor.author Zaslavsky, A.M.
dc.contributor.author Fann, J.R.
dc.contributor.author Rondon, M.B.
dc.contributor.author Sánchez, S.E.
dc.contributor.author Williams, M.A.
dc.date.accessioned 2019-04-24T18:23:57Z
dc.date.available 2019-04-24T18:23:57Z
dc.date.issued 2015
dc.identifier.uri https://hdl.handle.net/20.500.12866/6491
dc.description.abstract Objective: Generalized anxiety disorder (GAD) during pregnancy is associated with several adverse maternal and perinatal outcomes. A reliable and valid screening tool for GAD should lead to earlier detection and treatment. Among pregnant Peruvian women, a brief screening tool, the GAD-7, has not been validated. This study aims to evaluate the reliability and validity of the GAD-7. Methods: Of 2,978 women who attended their first perinatal care visit and had the GAD-7 screening, 946 had a Composite International Diagnostic Interview (CIDI). The Cronbach's alpha was calculated to examine the reliability. We assessed the criterion validity by calculating operating characteristics. The construct validity was evaluated using factor analysis and association with health status on the CIDI. The cross-cultural validity was explored using the Rasch Rating Scale Model (RSM). Results: The reliability of the GAD-7 was good (Cronbach' s alpha = 0.89). A cutoff score of 7 or higher, maximizing the Youden Index, yielded a sensitivity of 73.3%and a specificity of 67.3%. One-factor structure of the GAD-7 was confirmed by exploratory and confirmatory factor analysis. Concurrent validity was supported by the evidence that higher GAD-7 scores were associated with poor self-rated physical and mental health. The Rasch RSM further confirmed the cross-cultural validity of the GAD-7. Conclusion: The results suggest that the Spanish-language version of the GAD-7 may be used as a screening tool for pregnant Peruvian women. The GAD-7 has good reliability, factorial validity, and concurrent validity. The optimal cutoff score obtained by maximizing the Youden Index should be considered cautiously; women who screened positive may require further investigation to confirm GAD diagnosis. en_US
dc.language.iso eng
dc.publisher Public Library of Science
dc.relation.ispartofseries PLoS ONE
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject adult en_US
dc.subject Article en_US
dc.subject clinical assessment tool en_US
dc.subject cohort analysis en_US
dc.subject concurrent validity en_US
dc.subject construct validity en_US
dc.subject controlled study en_US
dc.subject criterion related validity en_US
dc.subject Cronbach alpha coefficient en_US
dc.subject cross-sectional study en_US
dc.subject cultural factor en_US
dc.subject factorial analysis en_US
dc.subject female en_US
dc.subject generalized anxiety disorder en_US
dc.subject Generalized Anxiety Disorder 7 en_US
dc.subject health status en_US
dc.subject human en_US
dc.subject interview en_US
dc.subject major clinical study en_US
dc.subject mental health en_US
dc.subject perinatal care en_US
dc.subject Peru en_US
dc.subject pregnant woman en_US
dc.subject prospective study en_US
dc.subject questionnaire en_US
dc.subject Rasch analysis en_US
dc.subject receiver operating characteristic en_US
dc.subject reliability en_US
dc.subject scoring system en_US
dc.subject screening test en_US
dc.subject self report en_US
dc.subject sensitivity and specificity en_US
dc.subject World Health Organization World Mental Health Composite International Diagnostic Interview en_US
dc.subject Youden index en_US
dc.subject adolescent en_US
dc.subject Anxiety Disorders en_US
dc.subject complication en_US
dc.subject middle aged en_US
dc.subject pregnancy en_US
dc.subject Pregnancy Complications en_US
dc.subject psychological interview en_US
dc.subject psychological rating scale en_US
dc.subject psychology en_US
dc.subject reproducibility en_US
dc.subject young adult en_US
dc.subject Adolescent en_US
dc.subject Adult en_US
dc.subject Anxiety Disorders en_US
dc.subject Cross-Cultural Comparison en_US
dc.subject Cross-Sectional Studies en_US
dc.subject Female en_US
dc.subject Humans en_US
dc.subject Interview, Psychological en_US
dc.subject Middle Aged en_US
dc.subject Peru en_US
dc.subject Pregnancy en_US
dc.subject Pregnancy Complications en_US
dc.subject Psychiatric Status Rating Scales en_US
dc.subject Reproducibility of Results en_US
dc.subject Young Adult en_US
dc.title Diagnostic validity of the generalized anxiety disorder - 7 (GAD-7) among pregnant women en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1371/journal.pone.0125096
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.02
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#5.01.00
dc.relation.issn 1932-6203


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