Universidad Peruana Cayetano Heredia

Oxfendazole as successful treatment of Taenia hydatigena metacestodes in naturally infected pigs

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dc.contributor.author Gomez-Puerta, L.A.
dc.contributor.author Gonzalez Zariquiey, Armando Emiliano
dc.contributor.author Gavidia, C.
dc.contributor.author Ayvar, V.
dc.contributor.author García Lescano, Héctor Hugo
dc.contributor.author Lopez-Urbina, M.T.
dc.date.accessioned 2019-04-25T15:46:34Z
dc.date.available 2019-04-25T15:46:34Z
dc.date.issued 2015
dc.identifier.uri https://hdl.handle.net/20.500.12866/6515
dc.description.abstract The efficacy of oxfendazole (OFZ) on Taenia hydatigena metacestodes, also called Cysticercus tenuicollis ( C. tenuicollis), was studied in 648 raising pigs. This study was performed in Tumbes Department in Peru, an endemic area for cysticercosis. Pigs were randomized in two groups; untreated group (. n = 142) did not receive any treatment and treated group ( n = 506) received OFZ treatment at a single dose of 30 mg/kg body weight. Six months after treatment, the pigs were necropsied. The prevalence of infection by C. tenuicollis among the pigs was 27.5% (39/142) and 2.0% (10/506) in untreated and treated groups, respectively. Untreated group was infested only with viable cysts, whereas treated group had no viable cysts. All the cysts found in treated group presented degeneration, with a thick membrane, and they contained milky fluid and fibrous tissue. A single dose of OFZ was effective against C. tenuicollis, thus providing an alternative drug for controlling this parasite in pigs. en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries Asian Pacific Journal of Tropical Biomedicine
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject oxfendazole en_US
dc.subject animal tissue en_US
dc.subject Article en_US
dc.subject controlled study en_US
dc.subject cyst en_US
dc.subject degeneration en_US
dc.subject drug efficacy en_US
dc.subject membrane en_US
dc.subject metacestode en_US
dc.subject nonhuman en_US
dc.subject Peru en_US
dc.subject pig en_US
dc.subject prevalence en_US
dc.subject priority journal en_US
dc.subject single drug dose en_US
dc.subject Taenia hydatigena en_US
dc.subject taeniasis en_US
dc.title Oxfendazole as successful treatment of Taenia hydatigena metacestodes in naturally infected pigs en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1016/j.apjtb.2015.03.013
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#1.06.03
dc.relation.issn 2588-9222


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