Universidad Peruana Cayetano Heredia

A multiple indicators multiple causes model of late-life depression in Latin American countries

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dc.contributor.author Brailean, A.
dc.contributor.author Guerra Arteaga, Mariella
dc.contributor.author Chua, K.-C.
dc.contributor.author Prince, M.
dc.contributor.author Prina, M.A.
dc.date.accessioned 2019-04-25T15:46:35Z
dc.date.available 2019-04-25T15:46:35Z
dc.date.issued 2015
dc.identifier.uri https://hdl.handle.net/20.500.12866/6520
dc.description.abstract Background: The Euro-D depression scale consists of symptom clusters that may be differentially related to demographic and cognitive characteristics in older adults. This hypothesis needs further investigation and the role of measurement bias on substantive conclusions remains to be established. Method: The study sample comprised 10,405 community-dwelling older adults from six Latin American countries. We applied a Multiple Indicators Multiple Causes (MIMIC) model for a concurrent investigation of measurement bias and of the association between Euro-D symptom clusters and background variables. Results: The factorial validity of Euro-D, with a two-dimensional structure - affective suffering and motivation disturbance, was consistently supported in all countries. Although complete measurement invariance could not be assumed across countries, measurement bias was minor. Both Euro-D factors were unrelated to age, but related to gender, as well as to impairment in memory and verbal fluency. Gender differences were larger for affective suffering than for motivation disturbance, whereas differences in verbal fluency impairment were more strongly related to motivation disturbance. Limitations: Our analytic strategies could only examine invariance at the level of indicator thresholds. The generalisability of current findings needs to be examined in clinical populations. A wider set of cognitive tests is needed. We did not examine the compositional factors that could have accounted for the variation in Euro-D scores across countries, as this was beyond the aims of the paper. Conclusion: The current study adds evidence for the construct validity of Euro-D and for the possible differential association of depression symptom-clusters with gender and verbal fluency in older adults. An understanding of the heterogeneity of late-life depression may carry clinical implications for the diagnosis and treatment of depression in old age. en_US
dc.language.iso eng
dc.publisher Elsevier
dc.relation.ispartofseries Journal of Affective Disorders
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject aged en_US
dc.subject Article en_US
dc.subject cognition en_US
dc.subject construct validity en_US
dc.subject depression assessment en_US
dc.subject executive function en_US
dc.subject female en_US
dc.subject human en_US
dc.subject late life depression en_US
dc.subject male en_US
dc.subject memory en_US
dc.subject motivation en_US
dc.subject Multiple Indicators Multiple Cause model en_US
dc.subject normal human en_US
dc.subject priority journal en_US
dc.subject semantic memory en_US
dc.subject sensitivity analysis en_US
dc.subject sex difference en_US
dc.subject South and Central America en_US
dc.subject adult en_US
dc.subject depression en_US
dc.subject middle aged en_US
dc.subject psychological model en_US
dc.subject psychological rating scale en_US
dc.subject psychology en_US
dc.subject risk factor en_US
dc.subject symptom assessment en_US
dc.subject very elderly en_US
dc.subject Adult en_US
dc.subject Aged en_US
dc.subject Aged, 80 and over en_US
dc.subject Depression en_US
dc.subject Female en_US
dc.subject Humans en_US
dc.subject Latin America en_US
dc.subject Male en_US
dc.subject Middle Aged en_US
dc.subject Models, Psychological en_US
dc.subject Motivation en_US
dc.subject Psychiatric Status Rating Scales en_US
dc.subject Risk Factors en_US
dc.subject Symptom Assessment en_US
dc.title A multiple indicators multiple causes model of late-life depression in Latin American countries en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1016/j.jad.2015.05.053
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.24
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#5.01.00
dc.relation.issn 1573-2517


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