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The status of cryptococcosis in latin America

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dc.contributor.author Firacative, C.
dc.contributor.author Lizarazo, J.
dc.contributor.author Illnait-Zaragozí, M.T.
dc.contributor.author Castañeda, Elizabeth
dc.contributor.author Arechavala, A.
dc.contributor.author Córdoba, S.
dc.contributor.author Mazza, M.
dc.contributor.author Taverna, C.
dc.contributor.author Isla, G.
dc.contributor.author Chiapello, L.
dc.contributor.author Vergara, M.L.S.
dc.contributor.author Melhem, M.S.C.
dc.contributor.author Szeszs, M.W.
dc.contributor.author Martins, M.A.
dc.contributor.author Bonfietti, L.X.
dc.contributor.author de Oliveira, R.A.
dc.contributor.author de Oliveira, L.
dc.contributor.author Santos, D.C.S.
dc.contributor.author Lazera, M.S.
dc.contributor.author Wanke, B.
dc.contributor.author Díaz, M.C.
dc.contributor.author Escandón, P.
dc.contributor.author Noguera, M.C.
dc.contributor.author Andreu, C.M.F.
dc.contributor.author Castrillón, L.
dc.contributor.author Bustamante Rufino, Ana Beatriz
dc.contributor.author Dolande, M.
dc.contributor.author Ferrara, G.
dc.contributor.author Latin American Cryptococcal Study Group
dc.date.accessioned 2019-04-25T15:46:36Z
dc.date.available 2019-04-25T15:46:36Z
dc.date.issued 2018
dc.identifier.uri https://hdl.handle.net/20.500.12866/6535
dc.description.abstract Cryptococcosis is a life-threatening fungal infection caused by the encapsulated yeasts Cryptococcus neoformans and C. gattii, acquired from the environment. In Latin America, as occurring worldwide, C. neoformans causes more than 90% of the cases of cryptococcosis, affecting predominantly patients with HIV, while C. gattii generally affects otherwise healthy individuals. In this region, cryptococcal meningitis is the most common presentation, with amphotericin B and fluconazole being the antifungal drugs of choice. Avian droppings are the predominant environmental reservoir of C. neoformans, while C. gattii is associated with several arboreal species. Importantly, C. gattii has a high prevalence in Latin America and has been proposed to be the likely origin of some C. gattii populations in North America. Thus, in the recent years, significant progress has been made with the study of the basic biology and laboratory identification of cryptococcal strains, in understanding their ecology, population genetics, host-pathogen interactions, and the clinical epidemiology of this important mycosis in Latin America. en_US
dc.language.iso eng
dc.publisher Fundacao Oswaldo Cruz
dc.relation.ispartofseries Memórias do Instituto Oswaldo Cruz
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject antifungal agent en_US
dc.subject AIDS related complex en_US
dc.subject cryptococcosis en_US
dc.subject human en_US
dc.subject South and Central America en_US
dc.subject AIDS-Related Opportunistic Infections en_US
dc.subject Antifungal Agents en_US
dc.subject Cryptococcosis en_US
dc.subject Humans en_US
dc.subject Latin America en_US
dc.title The status of cryptococcosis in latin America en_US
dc.type info:eu-repo/semantics/review
dc.identifier.doi https://doi.org/10.1590/0074-02760170554
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#1.06.01
dc.relation.issn 1678-8060


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