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Leiomyomatous Hamartomas of the Oral Cavity: Clinicopathological and Immunohistochemical Features of 4 Cases and Literature Review.

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dc.contributor.author Sanchez-Romero, Celeste
dc.contributor.author Bonan, Paulo Rogerio Ferreti
dc.contributor.author Pires, Fabio Ramoa
dc.contributor.author Oliveira Silva-Junior, Geraldo
dc.contributor.author Delgado Azanero, Wilson
dc.contributor.author de Almeida, Oslei Paes
dc.contributor.author da Cruz Perez, Danyel Elias
dc.date.accessioned 2019-07-04T17:00:17Z
dc.date.available 2019-07-04T17:00:17Z
dc.date.issued 2019
dc.identifier.uri https://hdl.handle.net/20.500.12866/6842
dc.description.abstract Objective. To present 4 new cases of oral leiomyomatous hamartomas (OLH), describing its clinical, microscopical, and immunohistochemical features, and a literature review. Methods. The OLH cases were retrieved from the files of 2 Brazilian and 1 Peruvian oral pathology services. Clinical data were obtained from the pathology reports. Microscopical features were reviewed, and immunohistochemical reactions were performed. A review of the English-language literature about OLH was done. Results. The sample was composed of 3 females (4-, 10-, and 15-year-old) and 1 male (3-year-old). Three cases affected the dorsum of the tongue and one the incisive papilla, and all presented sessile or pedunculated smooth nodules. Microscopically, the lesions were composed of varying-size fascicles of smooth muscle fibers in a fibrous connective tissue background. Immunohistochemistry revealed positivity of the smooth muscle bundles for myogenic markers. The English-language literature review revealed 38 OLH cases reported, most were congenital or diagnosed up to 5 years old. The main locations were tongue and anterior maxilla. Conclusions. Although OLH is a rare lesion, it must be considered in the differential diagnosis of midline tongue or maxillary masses in newborns, infants, and youngsters. en_US
dc.language.iso eng
dc.publisher SAGE Publications
dc.relation.ispartof urn:issn:1940-2465
dc.rights info:eu-repo/semantics/restrictedAccess
dc.rights.uri https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject adolescent en_US
dc.subject Brazilian en_US
dc.subject child en_US
dc.subject clinical article en_US
dc.subject clinical feature en_US
dc.subject English (language) en_US
dc.subject female en_US
dc.subject hamartoma en_US
dc.subject human en_US
dc.subject immunohistochemistry en_US
dc.subject leiomyoma en_US
dc.subject leiomyomatous en_US
dc.subject male en_US
dc.subject mouth tumor en_US
dc.subject oral en_US
dc.subject oral leiomyomatous hamartoma en_US
dc.subject Peruvian en_US
dc.subject preschool child en_US
dc.subject priority journal en_US
dc.subject Review en_US
dc.subject school child en_US
dc.subject smooth muscle cell en_US
dc.title Leiomyomatous Hamartomas of the Oral Cavity: Clinicopathological and Immunohistochemical Features of 4 Cases and Literature Review. en_US
dc.type info:eu-repo/semantics/article
dc.identifier.doi https://doi.org/10.1177/1066896919843337
dc.subject.ocde https://purl.org/pe-repo/ocde/ford#3.02.00 es_PE


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