Specific type IV pili groups in clinical isolates of Pseudomonas aeruginosa

Mosqueda, Noraida; Guerra, Humberto; Ruiz, Joaquim; Rubio, Mercedes; Horna, Gertrudis; Quezada, Karina; Ramos, Susan

dc.contributor.author	Horna, Gertrudis
dc.contributor.author	Quezada, Karina
dc.contributor.author	Ramos, Susan
dc.contributor.author	Mosqueda, Noraida
dc.contributor.author	Rubio, Mercedes
dc.contributor.author	Guerra, Humberto
dc.contributor.author	Ruiz, Joaquim
dc.date.accessioned	2019-07-04T17:01:20Z
dc.date.available	2019-07-04T17:01:20Z
dc.date.issued	2019
dc.identifier.uri	https://hdl.handle.net/20.500.12866/6910
dc.description.abstract	The relationships between specific type IV pili (TFP) groups and antibiotic resistance, biofilm formation, and bacterial motility were determined in 190 Pseudomonas aeruginosa clinical isolates. While motility and biofilm formation were determined by phenotypic assays, the presence of TFP was determined by PCR assay and antibiotic susceptibility by disk diffusion. The results showed a high ability to form biofilm (97.4%), multidrug resistance (44.7%), and the presence of a high number of motile isolates. We also found an association between strong biofilm production and multidrug resistance. Furthermore, TFP group III was associated with strong biofilm production. In contrast, the isolates with TFP group II and those without any TFP were associated with non-strong biofilm production. Regarding motility, TFP group II was associated with higher percentages of swarming, swimming, and twitching, while TFP group I showed lower percentages of swarming and twitching, and TFP group III showed lower levels of swarming and swimming. In conclusion, these findings highlight the differences in P. aeruginosa phenotypes related to the presence of specific TFP groups and their potential implications in clinical settings.	en_US
dc.language.iso	eng
dc.publisher	Springer
dc.relation.ispartofseries	International Microbiology
dc.rights	info:eu-repo/semantics/restrictedAccess
dc.rights.uri	https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
dc.subject	Anti-Bacterial Agents	en_US
dc.subject	antibiotic resistance	en_US
dc.subject	antiinfective agent	en_US
dc.subject	Bacterial motility	en_US
dc.subject	biofilm	en_US
dc.subject	Biofilm	en_US
dc.subject	Biofilms	en_US
dc.subject	disk diffusion	en_US
dc.subject	Disk Diffusion Antimicrobial Tests	en_US
dc.subject	drug effect	en_US
dc.subject	Drug Resistance, Bacterial	en_US
dc.subject	fimbria	en_US
dc.subject	Fimbriae, Bacterial	en_US
dc.subject	genetics	en_US
dc.subject	growth, development and aging	en_US
dc.subject	human	en_US
dc.subject	Humans	en_US
dc.subject	isolation and purification	en_US
dc.subject	locomotion	en_US
dc.subject	Locomotion	en_US
dc.subject	microbiology	en_US
dc.subject	Multidrug resistance	en_US
dc.subject	physiology	en_US
dc.subject	polymerase chain reaction	en_US
dc.subject	Polymerase Chain Reaction	en_US
dc.subject	Pseudomonas aeruginosa	en_US
dc.subject	Pseudomonas infection	en_US
dc.subject	Pseudomonas Infections	en_US
dc.subject	Swarming	en_US
dc.subject	Swimming	en_US
dc.subject	Twitching	en_US
dc.title	Specific type IV pili groups in clinical isolates of Pseudomonas aeruginosa	en_US
dc.type	info:eu-repo/semantics/article
dc.identifier.doi	https://doi.org/10.1007/s10123-018-00035-3
dc.subject.ocde	https://purl.org/pe-repo/ocde/ford#1.06.01
dc.relation.issn	1618-1905